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Anti-Prostate Specific Antigen抗体- Catalytic domain (ab40949)

Submit a review Q&A (1)References (1)
Western blot - Anti-Prostate Specific Antigen antibody - Catalytic domain (ab40949)

    Key features and details

    • Rabbit polyclonal to Prostate Specific Antigen - Catalytic domain
    • Suitable for: WB
    • Reacts with: Human
    • Isotype: IgG

    概述

    • 产品名称

      Anti-Prostate Specific Antigen抗体- Catalytic domain
      参阅全部 Prostate Specific Antigen 一抗

    • 描述

      兔多克隆抗体to Prostate Specific Antigen - Catalytic domain

    • 宿主

      Rabbit

    • 特异性

      This antibody is specific for Kallikrein 3, it does not react with the other Kallikreins (1,2,4-15).

    • 经测试应用

      适用于: WBmore details

    • 种属反应性

      与反应: Human

    • 免疫原

      Synthetic peptide based on the catalytic domain of human Kallikrein 3. (Peptide available as ab43085.)

    • 常规说明

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    性能

    应用

    The Abpromise guarantee

    Abpromise™承诺保证使用ab40949于以下的经测试应用

    “应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。

    应用 Ab评论 说明
    WB
    1/1000. Predicted molecular weight: 29 kDa. 1/1000 when using colorimetric substrates such as BCIP/NBT and 1/5000 for chemiluminescent substrates. Predicted molecular weight: 29 kDa. Dilution optimised using Chromogenic detection.
    说明
    WB
    1/1000. Predicted molecular weight: 29 kDa. 1/1000 when using colorimetric substrates such as BCIP/NBT and 1/5000 for chemiluminescent substrates. Predicted molecular weight: 29 kDa. Dilution optimised using Chromogenic detection.

    靶标

    • 功能

      Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.

    • 序列相似性

      Belongs to the peptidase S1 family. Kallikrein subfamily.
      Contains 1 peptidase S1 domain.

    • 细胞定位

      Secreted.
    • Information by UniProt

    • 数据库链接

      • 别名

        • antigen, prostate-specific antibody
        • APS antibody
        • Gamma seminoprotein antibody
        • Gamma-seminoprotein antibody
        • hK3 antibody
        • Kallikrein 3 antibody
        • Kallikrein related peptidase 3 antibody
        • Kallikrein-3 antibody
        • KLK 3 antibody
        • KLK2A1 antibody
        • Klk3 antibody
        • KLK3_HUMAN antibody
        • P-30 antigen antibody
        • P30 antigen antibody
        • Prostate-specific antigen antibody
        • Psa antibody
        • Semenogelase antibody
        • Seminin antibody
        see all

      图片

      • Western blot - Anti-Prostate Specific Antigen antibody - Catalytic domain (ab40949)
        Western blot - Anti-Prostate Specific Antigen antibody - Catalytic domain (ab40949)
        All lanes : Anti-Prostate Specific Antigen antibody - Catalytic domain (ab40949) at 1/1000 dilution

        Lane 1 : Human Kallikrein 3 at 0.05 µg
        Lane 2 : Human Kallikrein 3 at 0.01 µg
        Lane 3 : Human Kallikrein 3 at 0.001 µg

        Predicted band size: 29 kDa
        Observed band size: 33 kDa why is the actual band size different from the predicted?

      文献 (1)

      发表研究结果有使用 ab40949？请让我们知道，以便我们可以引用本数据表中的参考文章。

      ab40949 被引用在 1 文献中.

      • Johnson IR  et al. Prostate cell lines as models for biomarker discovery: performance of current markers and the search for new biomarkers. Prostate 74:547-60 (2014). PubMed: 24435746

      客户评价及客户问答

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      Question


      Human PSA protein and anti-PSA antibody

      I have found many products related to PSA(prostrate specific antigen), one product has been found , having its antibody with it. the catalog # no is (ab 41421) , product description : prostrate specific antigen peptide (Kallikrein loop), used as an immunogen for (ab 28563-kallikrein 3Ab-kallikrein loop.), .

      2nd product is PSA peptide (244-254) (ab 45800) having seq. c-termina lhuman PSA, it is used as an immunogen for ab 39983-PSA Ab. but this antibody product is not available.Can you please suggest me any alternate for this .

      Please also confirm about their specific reactivity with each other.

      Read More
      Answer


      Another antibody/peptide combination is Anti-Prostate Specific Antigen antibody - Catalytic domain (ab40949) / Prostate Specific Antigen peptide (Catalytic domain) (ab43085).
      Regarding your question: "Please also confirm about their specific reactivity with each other."
      I think you are wondering if any of the peptides you mention will react with the other PSA antibodies. For the specific antibody/peptide pairs you note, the antibodies will be specific only for their cognate peptide. These peptide immunogens are short, 10-20 amino acid peptides.

      Read More

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