重组Anti-Prostate Secretory蛋白/PSP抗体[EPR7346] (ab133296)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Prostate Secretory Protein/PSP antibody [EPR7346] (ab133296)](https://www.abcam.cn/ps/products/133/ab133296/Images/Prostate-Secretory-ProteinPSP-Primary-antibodies-ab133296-2.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Prostate Secretory Protein/PSP antibody [EPR7346] (ab133296)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR7346] to Prostate Secretory Protein/PSP
- Suitable for: WB, IHC-P
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-Prostate Secretory蛋白/PSP抗体[EPR7346]
参阅全部 Prostate Secretory Protein/PSP 一抗 -
描述
兔单克隆抗体[EPR7346] to Prostate Secretory蛋白/PSP -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details
不适用于: ICC/IF or IP -
种属反应性
与反应: Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- human prostate cancer, human prostate tissue
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. -
解离常数（KD）
KD = 7.11 x 10 -10 M Learn more about KD -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading... -
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EPR7346 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab133296于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/10000 - 1/50000. Detects a band of approximately 16 kDa (predicted molecular weight: 13 kDa).
|
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| IHC-P |
1/250 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
|
| 说明 |
|---|
|
WB
1/10000 - 1/50000. Detects a band of approximately 16 kDa (predicted molecular weight: 13 kDa). |
|
IHC-P
1/250 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
应用说明
Is unsuitable for ICC/IF or IP.
靶标
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组织特异性
Strongly expressed in prostate, liver, kidney, breast and penis. Also expressed in pancreas, esophagus, stomach, deodenum, colon, trachea, lung, salivary glands and fallopian tube. PSP94 is expressed in lung and breast, whereas PSP57 is found in kidney and bladder. -
疾病相关
Defects in MSMB are the cause of susceptibility to prostate cancer hereditary type 13 (HPC13) [MIM:611928]. It is a condition associated with familial predisposition to cancer of the prostate. Most prostate cancers are adenocarcinomas that develop in the acini of the prostatic ducts. Other rare histopathologic types of prostate cancer that occur in approximately 5% of patients include small cell carcinoma, mucinous carcinoma, prostatic ductal carcinoma, transitional cell carcinoma, squamous cell carcinoma, basal cell carcinoma, adenoid cystic carcinoma (basaloid), signet-ring cell carcinoma and neuroendocrine carcinoma. -
序列相似性
Belongs to the beta-microseminoprotein family. -
细胞定位
Secreted. Sperm surface. - Information by UniProt
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数据库链接
- Entrez Gene: 4477 Human
- Omim: 157145 Human
- SwissProt: P08118 Human
- Unigene: 255462 Human
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别名
- Beta microseminoprotein [Precursor] antibody
- Beta-microseminoprotein antibody
- HPC 13 antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Prostate Secretory Protein/PSP antibody [EPR7346] (ab133296)
Immunohistochemical analysis of paraffin-embedded Human prostate tissue labelling Prostate Secretory Protein/PSP with 1/250 ab133296.
Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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![Western blot - Anti-Prostate Secretory Protein/PSP antibody [EPR7346] (ab133296)](https://www.abcam.cn/ps/products/133/ab133296/Images/Prostate-Secretory-ProteinPSP-Primary-antibodies-ab133296-1.JPG)
Western blot - Anti-Prostate Secretory Protein/PSP antibody [EPR7346] (ab133296)All lanes : Anti-Prostate Secretory Protein/PSP antibody [EPR7346] (ab133296) at 1/10000 dilution
Lane 1 : Human prostate cancer lysate
Lane 2 : Human prostate lysate
Lysates/proteins at 10 µg per lane.
Predicted band size: 13 kDa
Observed band size: 16 kDa why is the actual band size different from the predicted? -
![OI-RD Scanning - Anti-Prostate Secretory Protein/PSP antibody [EPR7346] (ab133296)](https://www.abcam.cn/ps/products/133/ab133296/Images/Prostate-Secretory-ProteinPSP-Primary-antibodies-ab133296-3.jpg)
OI-RD Scanning - Anti-Prostate Secretory Protein/PSP antibody [EPR7346] (ab133296) -
![Anti-Prostate Secretory Protein/PSP antibody [EPR7346] (ab133296)](https://www.abcam.cn/ps/products/133/ab133296/Images/ab133296-4-benefits-of-recombinant-antibodies.png)
Anti-Prostate Secretory Protein/PSP antibody [EPR7346] (ab133296)
数据表及文件
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SDS download
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Datasheet download
文献 (0)
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