Anti-Prostaglandin E Receptor EP1/PTGER1抗体(ab183073)
Key features and details
- Rabbit polyclonal to Prostaglandin E Receptor EP1/PTGER1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Prostaglandin E Receptor EP1/PTGER1抗体
参阅全部 Prostaglandin E Receptor EP1/PTGER1 一抗 -
描述
兔多克隆抗体to Prostaglandin E Receptor EP1/PTGER1 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat -
免疫原
Synthetic peptide within Human Prostaglandin E Receptor EP1/PTGER1 aa 350 to the C-terminus. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements. Genbank: NP_000946
Database link: P34995 -
阳性对照
- 293T cell lysate, Human lymphoma tissue lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS
(PBS is without Mg2+ and Ca2+ -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab183073于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB | (1) |
1/450 - 1/5000. Predicted molecular weight: 42 kDa.
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说明 |
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WB
1/450 - 1/5000. Predicted molecular weight: 42 kDa. |
靶标
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相关性
PTGER1 is a subtype 1 receptor for prostaglandin E2 (PGE2). This receptor is coupled to the phosphatidylinositol-calcium second messenger system by G(q) proteins. PTGER1 may be an important modulator of renal function and is implicated in the smooth muscle contractile response to PGE2 in various tissues. -
细胞定位
Cell Membrane; multi-pass membrane protein. -
数据库链接
- Entrez Gene: 5731 Human
- Entrez Gene: 19216 Mouse
- Entrez Gene: 25637 Rat
- Omim: 176802 Human
- SwissProt: P34995 Human
- SwissProt: P35375 Mouse
- SwissProt: P70597 Rat
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别名
- EP1 antibody
- PGE receptor EP1 subtype antibody
- PGE2 receptor EP1 subtype antibody
see all
图片
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All lanes : Anti-Prostaglandin E Receptor EP1/PTGER1 antibody (ab183073) at 1/450 dilution
Lane 1 : Human lymphoma tissue lysate
Lane 2 : 293T cell lysate
Lysates/proteins at 40 µg per lane.
Secondary
All lanes : Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution
Developed using the ECL technique.
Predicted band size: 42 kDa
Exposure time: 1 minute10%SDS-PAGE
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab183073 被引用在 2 文献中.
- Kowalczyk-Zieba I et al. Hypothyroidism Affects Uterine Function via the Modulation of Prostaglandin Signaling. Animals (Basel) 11:N/A (2021). PubMed: 34573602
- Lu JW et al. Activation of prostaglandin EP4 receptor attenuates the induction of cyclooxygenase-2 expression by EP2 receptor activation in human amnion fibroblasts: implications for parturition. FASEB J 33:8148-8160 (2019). PubMed: 30917001