Anti-Prolyl Endopeptidase抗体(ab58988)
Key features and details
- Rabbit polyclonal to Prolyl Endopeptidase
- Suitable for: WB
- Reacts with: Dog
- Isotype: IgG
概述
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产品名称
Anti-Prolyl Endopeptidase抗体
参阅全部 Prolyl Endopeptidase 一抗 -
描述
兔多克隆抗体to Prolyl Endopeptidase -
宿主
Rabbit -
特异性
ab58988 does not recognize other Prolyl Endopeptidase family members. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Dog -
免疫原
Synthetic peptide based on the amino terminal end of human Prolyl Endopeptidase. (Peptide available as ab63973.) Immunizing peptide available on request, please contact a customer service representative to ask for availability.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: PBS, 50% Glycerol, 2.9% Sodium chloride -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab58988于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
说明 |
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A recommended starting concentration for Western blots is 1:1,000 when using colorimetric substrates such as BCIP/NBT, and 1:5,000 for chemiluminescent substrates.
EDTA/EGTA treatment of tissues or lysates is required to see latent zymogen.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
靶标
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功能
Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long. -
序列相似性
Belongs to the peptidase S9A family. -
翻译后修饰
The N-terminus is blocked. -
细胞定位
Cytoplasm. - Information by UniProt
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别名
- dJ355L5.1 (prolyl endopeptidase) antibody
- HGNC:9358 antibody
- MGC16060 antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (22)
ab58988 被引用在 22 文献中.
- Zhang JB et al. Therapeutic Effect of Prolyl Endopeptidase Inhibitor in High-fat Diet-induced Metabolic Dysfunction-associated Fatty Liver Disease. J Clin Transl Hepatol 11:1035-1049 (2023). PubMed: 37577240
- Lin SZ et al. Prolyl endopeptidase remodels macrophage function as a novel transcriptional coregulator and inhibits fibrosis. Exp Mol Med 55:1437-1450 (2023). PubMed: 37394591
- Kilpeläinen TP et al. Nonpeptidic Oxazole-Based Prolyl Oligopeptidase Ligands with Disease-Modifying Effects on α-Synuclein Mouse Models of Parkinson's Disease. J Med Chem 66:7475-7496 (2023). PubMed: 37248563
- Hellinen L et al. Inhibition of prolyl oligopeptidase: A promising pathway to prevent the progression of age-related macular degeneration. Biomed Pharmacother 146:112501 (2022). PubMed: 34891119
- Minucci S & Venditti M New Insight on the In Vitro Effects of Melatonin in Preserving Human Sperm Quality. Int J Mol Sci 23:N/A (2022). PubMed: 35563519