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Anti-Progesterone抗体[11P14] (ab20236)

Submit a review Q&A (1)References (1)

Key features and details

  • Mouse monoclonal [11P14] to Progesterone
  • Suitable for: RIA
  • Reacts with: Human
  • Isotype: IgG2b

概述

  • 产品名称

    Anti-Progesterone抗体[11P14]
    参阅全部 Progesterone 一抗

  • 描述

    小鼠单克隆抗体[11P14] to Progesterone

  • 宿主

    Mouse

  • 经测试应用

    适用于: RIAmore details

  • 种属反应性

    与反应: Human

  • 免疫原

    11a-Hydroxyprogesterone conjugated to bovine serum albumin.

  • 常规说明

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

性能

  • 形式

    Liquid

  • 存放说明

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

  • 存储溶液

    Preservative: 0.02% Sodium azide
    Constituent: 99.98% PBS
  • Concentration information loading...

  • 纯度

    Protein A/G purified

  • 克隆

    单克隆

  • 克隆编号

    11P14

  • 骨髓瘤

    P3-NS1/1-Ag4-1

  • 同种型

    IgG2b

  • 轻链类型

    unknown

  • 研究领域

应用

The Abpromise guarantee

Abpromise™承诺保证使用ab20236于以下的经测试应用

“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。

应用 Ab评论 说明
RIA
Use at an assay dependent concentration.
说明
RIA
Use at an assay dependent concentration.

靶标

  • 相关性

    Progesterone plays a central role in the reproductive events associated with the establishment and maintenance of pregnancy. Progesterone receptor, a member of the steroid receptor superfamily, mediates the physiologic effects of progesterone. The PGR gene uses separate promoters and translational start sites to produce 2 isoforms, PRA and PRB, which are identical except for an additional 165 amino acids present only in the N terminus of PRB. Although PRA and PRB share several structural domains, they are distinct transcription factors that mediate their own response genes and physiologic effects with little overlap. It is composed of three domains: a modulating N terminal domain, a DNA binding domain and a C terminal steroid binding domain. Progesterone levels 1. men 30-60 pg/0.1ml 2. women pre ovulatory phase: 20-160 pg/0.1ml; ovulatory phase: 1,000-1,700 pg/0.1ml; post ovulatory phase: 1,000-1,700 pg/0.1ml; Pregnant: 16-18 weeks: 300-800 pg/0.1ml; 28-30 weeks: 6,500-14,700 pg/0.1ml; 38-40 weeks: 12,000-19,000 pg/0.1ml.

  • 细胞定位

    Secreted

  • 别名

    • Pregn 4 ene 3 20 dione antibody

实验方案

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

文献 (1)

发表研究结果有使用 ab20236？请让我们知道，以便我们可以引用本数据表中的参考文章。

ab20236 被引用在 1 文献中.

  • Fantl VE  et al. The production of high affinity monoclonal antibodies to progesterone. J Steroid Biochem 17:125-30 (1982). PubMed: 7109599

客户评价及客户问答

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Question

Dear Sir or Madam, Our company would like to order an monoclonal antibody for progesterone determination. Your company offer many different types of progesterone antibodies and I am not sure which one could be best. We need to develop ELISA test for determination of progesterone at cows. You determine species reactivity mostly for human. I think it should be same for other species, like cow, but I would like if you can confirm it. We need to have good reactivity with natural progesterone and for Progesterone 3-(O-carboxymethyl)oxime conjugate. Please can you offer me most suitable antibody for this purpose  and add more informations about possible package, price and delivery term. If I forgot any necessary informations you need, please let me know. Thank you very much for answer. Best regards  

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Answer

Thank you for contacting us. We do have anti progesterone antibodies available in catalogue. These however are tested with human samples only. Cow is an untested species so we cannot provide any tested data to confirm its cross reactivity. It is more likely that these antibodies will detect Cow harmone also. If you are interested in using one of the progesterone antibodies with COW samples I can offer you an Abreview discount code. This discount code will give you next primary antibody free of charge in exchange of an Abreview. The discount code will still be valid no matter the results are positive or negative. Let me know if you are interested then I will send you the discount code. The anti progesterone antibodies we have are ab1977, ab6060, ab9187, ab9188, ab20236, ab80706 etc. Full list can be found by clicking following link; https://www.abcam.com/index.html?pageconfig=searchresults&pt=1&search=progesterone For Progesterone 3-(O-carboxymethyl) oxime we have ab53985 available in catalogue; https://www.abcam.com/4-Pregnen-3-20-Dione-3-O-Carboxymethyloxime-antibody-ab53985.html Please be advised that anti progesterone antibodies are only tested in indirect ELISA procedure we do not have information of matched sandwich ELISA pairs so sELISA is not a guaranteed application. We generally provide next day delivery in Euorpe. For price of these antibodies please visit our homepage and select your home country at top of the page; the website will automatically give you the information of price and delivery charges. I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

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