重组人AANAT蛋白(Tagged) (ab239443)
Key features and details
- Expression system: Escherichia coli
- Purity: > 85% SDS-PAGE
- Tags: His tag N-Terminus, GST tag N-Terminus
- Suitable for: SDS-PAGE
描述
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产品名称
重组人AANAT蛋白(Tagged)
参阅全部 AANAT 蛋白酶 -
纯度
> 85 % SDS-PAGE. -
表达系统
Escherichia coli -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MSTQSTHPLKPEAPRLPPGIPESPSCQRRHTLPASEFRCLTPEDAVSAFE IEREAFISVLGVCPLYLDEIRHFLTLCPELSLGWFEEGCLVAFIIGSLWD KERLMQESLTLHRSGGHIAHLHVLAVHRAFRQQGRGPILLWRYLHHLGSQ PAVRRAALMCEDALVPFYERFSFHAVGPCAITVGSLTFMELHCSLRGHPF LRRNSGC -
预测分子量
52 kDa including tags -
氨基酸
1 to 207 -
标签
His tag N-Terminus , GST tag N-Terminus -
额外的序列信息
N-terminal 10xHis-GST-tagged.
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab239443 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
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形式
Liquid -
补充说明
This product was previously labelled as Serotonin N-acetyltransferase
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.2
Constituents: Tris buffer, 50% Glycerol (glycerin, glycerine)
常规信息
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别名
- AA-NAT
- Aanat
- Aralkylamine N-acetyltransferase
see all -
功能
Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin. -
组织特异性
Highly expressed in pineal gland and at lower levels in the retina. Weak expression in several brain regions and in the pituitary gland. -
通路
Aromatic compound metabolism; melatonin biosynthesis; melatonin from serotonin: step 1/2. -
疾病相关
Delayed sleep phase syndrome -
序列相似性
Belongs to the acetyltransferase family. AANAT subfamily.
Contains 1 N-acetyltransferase domain. -
翻译后修饰
cAMP-dependent phosphorylation on both N-terminal Thr-31 and C-terminal Ser-205 regulates AANAT activity by promoting interaction with 14-3-3 proteins. -
细胞定位
Cytoplasm. - Information by UniProt
图片
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab239443 尚未被引用在任何文献中。