Anti-PRDM4/PFM1抗体(ab126939)
Key features and details
- Rabbit polyclonal to PRDM4/PFM1
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-PRDM4/PFM1抗体
参阅全部 PRDM4/PFM1 一抗 -
描述
兔多克隆抗体to PRDM4/PFM1 -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Mouse, Human -
免疫原
Recombinant fragment, corresponding to a region within amino acids 559-758 of Human PRDM4/PFM1 (Q9UKN5).
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阳性对照
- PC3 and U-87 MG whole cell lysate; Human HBL435 xenograft and Mouse Muscle tissues.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab126939于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/1000 - 1/10000. Predicted molecular weight: 88 kDa.
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| IHC-P |
1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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| 说明 |
|---|
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WB
1/1000 - 1/10000. Predicted molecular weight: 88 kDa. |
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IHC-P
1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
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功能
May function as a transcription factor involved in cell differentiation. -
组织特异性
Expressed in many tissues. Highly expressed in ovary, testis, pancreas, brain, heart and prostate. -
序列相似性
Contains 6 C2H2-type zinc fingers.
Contains 1 SET domain. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 11108 Human
- Entrez Gene: 72843 Mouse
- Omim: 605780 Human
- SwissProt: Q9UKN5 Human
- SwissProt: Q80V63 Mouse
- Unigene: 506655 Human
- Unigene: 25307 Mouse
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别名
- MGC45046 antibody
- PFM 1 antibody
- PFM1 antibody
see all
图片
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Western blot - Anti-PRDM4/PFM1 antibody (ab126939)All lanes : Anti-PRDM4/PFM1 antibody (ab126939) at 1/5000 dilution
Lane 1 : PC3 whole cell lysate
Lane 2 : U-87 MG whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 88 kDa
7.5% SDS PAGE -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PRDM4/PFM1 antibody (ab126939)ab126939, at 1/500 dilution, staining PRDM4/PFM1 in Paraffin-embedded Human HBL435 xenograft tissue by Immunohistochemistry. -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PRDM4/PFM1 antibody (ab126939)ab126939, at 1/500 dilution, staining PRDM4/PFM1 in Paraffin-embedded Mouse Muscle tissue by Immunohistochemistry.
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab126939 被引用在 1 文献中.
- Yang WT et al. PRDM4 inhibits cell proliferation and tumorigenesis by inactivating the PI3K/AKT signaling pathway through targeting of PTEN in cervical carcinoma. Oncogene 40:3318-3330 (2021). PubMed: 33846573