重组Anti-PPAR delta抗体[EPR5185(2)] (ab173299)
![Western blot - Anti-PPAR delta antibody [EPR5185(2)] (ab173299)](https://www.abcam.cn/ps/products/173/ab173299/Images/ab173299-196728-anti-ppar-delta-antibody-epr51852-western-blot.jpg "Western blot - Anti-PPAR delta antibody [EPR5185(2)] (ab173299)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR5185(2)] to PPAR delta
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-PPAR delta抗体[EPR5185(2)]
参阅全部 PPAR delta 一抗 -
描述
兔单克隆抗体[EPR5185(2)] to PPAR delta -
宿主
Rabbit -
经测试应用
适用于: WBmore details
不适用于: Flow Cyt,ICC/IF,IHC-P or IP -
种属反应性
与反应: Human -
免疫原
Synthetic peptide within Human PPAR delta aa 150-250 (Cysteine residue). The exact sequence is proprietary.
Database link: Q03181 -
阳性对照
- HCT-116, K562, and Jurkat cell lysates
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading... -
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EPR5185(2) -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab173299于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/1000 - 1/5000. Detects a band of approximately 52 kDa (predicted molecular weight: 50 kDa).
|
| 说明 |
|---|
|
WB
1/1000 - 1/5000. Detects a band of approximately 52 kDa (predicted molecular weight: 50 kDa). |
应用说明
Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
靶标
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功能
Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand. -
组织特异性
Ubiquitous with maximal levels in placenta and skeletal muscle. -
序列相似性
Belongs to the nuclear hormone receptor family. NR1 subfamily.
Contains 1 nuclear receptor DNA-binding domain. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 5467 Human
- Omim: 600409 Human
- SwissProt: Q03181 Human
- Unigene: 696032 Human
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别名
- FAAR antibody
- MGC3931 antibody
- NR1C2 antibody
see all
图片
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Western blot - Anti-PPAR delta antibody [EPR5185(2)] (ab173299)All lanes : Anti-PPAR delta antibody [EPR5185(2)] (ab173299) at 1/1000 dilution
Lane 1 : HCT-116 cell lysate
Lane 2 : K562 cell lysate
Lane 3 : Jurkat cell lysate
Lysates/proteins at 10 µg per lane.
Predicted band size: 50 kDa
Additional bands at: 52 kDa. We are unsure as to the identity of these extra bands. -
![Anti-PPAR delta antibody [EPR5185(2)] (ab173299)](https://www.abcam.cn/ps/products/173/ab173299/Images/ab173299-2-benefits-of-recombinant-antibodies.png)
Anti-PPAR delta antibody [EPR5185(2)] (ab173299)
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab173299 尚未被引用在任何文献中。