Anti-PLEK2抗体(ab121131)
Key features and details
- Rabbit polyclonal to PLEK2
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-PLEK2抗体 -
描述
兔多克隆抗体to PLEK2 -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse
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免疫原
Recombinant fragment, corresponding to amino acids 237-346 of Human PLEK2 (Q9NYT0).
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阳性对照
- IHC-P: Human small intestine, liver and pancreas tissues.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab121131于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Retrieval buffer pH 6.
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| 说明 |
|---|
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IHC-P
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Retrieval buffer pH 6. |
靶标
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功能
May help orchestrate cytoskeletal arrangement. Contribute to lamellipodia formation. -
序列相似性
Contains 1 DEP domain.
Contains 2 PH domains. -
细胞定位
Cell projection > lamellipodium membrane. Cytoplasm > cytoskeleton. - Information by UniProt
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数据库链接
- Entrez Gene: 26499 Human
- Entrez Gene: 27260 Mouse
- Omim: 608007 Human
- SwissProt: Q9NYT0 Human
- SwissProt: Q9WV52 Mouse
- Unigene: 170473 Human
- Unigene: 103380 Mouse
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别名
- Pleckstrin 2 (mouse) homolog antibody
- Pleckstrin 2 antibody
- Pleckstrin-2 antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PLEK2 antibody (ab121131)
Immunohistochemical analysis of formalin-fixed, paraffin-embedded human small intestine tissue labeling PLEK2 with ab121131 at a 1/200 dilution.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PLEK2 antibody (ab121131)Immunohistochemical analysis of formalin-fixed, paraffin-embedded human liver tissue labeling PLEK2 with ab121131 at a 1/200 dilution.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PLEK2 antibody (ab121131)Immunohistochemical analysis of formalin-fixed, paraffin-embedded human pancreas tissue labeling PLEK2 with ab121131 at a 1/200 dilution.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PLEK2 antibody (ab121131)Immunohistochemical analysis of formalin-fixed, paraffin-embedded human skeletal muscle tissue labeling PLEK2 with ab121131 at a 1/200 dilution. No positivity observed.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab121131 被引用在 2 文献中.
- Zhou Y et al. Identification of a three-gene expression signature and construction of a prognostic nomogram predicting overall survival in lung adenocarcinoma based on TCGA and GEO databases. Transl Lung Cancer Res 11:1479-1496 (2022). PubMed: 35958325
- Chai B et al. Pleckstrin 2 is a potential drug target for colorectal carcinoma with activation of APC/β‑catenin. Mol Med Rep 24:N/A (2021). PubMed: 34676872