重组Anti-Pirin/PIR抗体[EPR11376] (ab172629)
![Western blot - Anti-Pirin/PIR antibody [EPR11376] (ab172629)](https://www.abcam.cn/ps/products/172/ab172629/Images/ab172629-196035-anti-pirin-pir-antibody-epr11376-western-blot.jpg "Western blot - Anti-Pirin/PIR antibody [EPR11376] (ab172629)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR11376] to Pirin/PIR
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-Pirin/PIR抗体[EPR11376]
参阅全部 Pirin/PIR 一抗 -
描述
兔单克隆抗体[EPR11376] to Pirin/PIR -
宿主
Rabbit -
经测试应用
适用于: WBmore details
不适用于: Flow Cyt,ICC/IF,IHC-P or IP -
种属反应性
与反应: Human
预测可用于: Mouse, Rat
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免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- MCF-7, HeLa and HepG2 cell lysates.
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading... -
纯度
Tissue culture supernatant -
克隆
单克隆 -
克隆编号
EPR11376 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab172629于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/1000 - 1/10000. Predicted molecular weight: 32 kDa.
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| 说明 |
|---|
|
WB
1/1000 - 1/10000. Predicted molecular weight: 32 kDa. |
应用说明
Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
靶标
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功能
Possible transcriptional coregulator. May contribute to the regulation of cellular processes via its interaction with BCL3. May be required for efficient terminal myeloid maturation of hematopoietic cells. May play a role in the regulation of cell migration. May promote apoptosis when overexpressed. Has quercetin 2,3-dioxygenase activity (in vitro). -
组织特异性
Highly expressed in a subset of melanomas. Detected at very low levels in most tissues (at protein level). Expressed in all tissues, with highest level of expression in heart and liver. -
通路
Flavonoid metabolism; quercetin degradation. -
序列相似性
Belongs to the pirin family. -
细胞定位
Nucleus. Cytoplasm. Predominantly localized in dot-like subnuclear structures. Cytoplasmic localization of PIR seems to positively correlate with melanoma progression. - Information by UniProt
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数据库链接
- Entrez Gene: 8544 Human
- Entrez Gene: 69656 Mouse
- Entrez Gene: 363465 Rat
- Omim: 603329 Human
- SwissProt: O00625 Human
- SwissProt: Q9D711 Mouse
- SwissProt: Q5M827 Rat
- Unigene: 495728 Human
see all -
别名
- 3-dioxygenase PIR antibody
- Iron binding nuclear protein antibody
- Pir antibody
see all
图片
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Western blot - Anti-Pirin/PIR antibody [EPR11376] (ab172629)All lanes : Anti-Pirin/PIR antibody [EPR11376] (ab172629) at 1/1000 dilution
Lane 1 : MCF-7 cell lysate
Lane 2 : HeLa cell lysate
Lane 3 : HepG2 cell lysate
Lysates/proteins at 10 µg per lane.
Predicted band size: 32 kDa -
![Anti-Pirin/PIR antibody [EPR11376] (ab172629)](https://www.abcam.cn/ps/products/172/ab172629/Images/ab172629-2-benefits-of-recombinant-antibodies.png)
Anti-Pirin/PIR antibody [EPR11376] (ab172629)
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab172629 尚未被引用在任何文献中。