重组Anti-Pin1 (phospho S16)抗体[EP1480Y] (ab62378)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EP1480Y] to Pin1 (phospho S16)
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-Pin1 (phospho S16)抗体[EP1480Y]
参阅全部 Pin1 一抗 -
描述
兔单克隆抗体[EP1480Y] to Pin1 (phospho S16) -
宿主
Rabbit -
经测试应用
适用于: WBmore details
不适用于: Flow Cyt or IP -
种属反应性
与反应: Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- HeLa cell lysate.
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EP1480Y -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab62378于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
1/500. Detects a band of approximately 18 kDa (predicted molecular weight: 18 kDa).
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说明 |
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WB
1/500. Detects a band of approximately 18 kDa (predicted molecular weight: 18 kDa). |
靶标
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功能
Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzing pSer/Thr-Pro cis/trans isomerizations. -
序列相似性
Contains 1 PpiC domain.
Contains 1 WW domain. -
结构域
The WW domain is required for the interaction with STIL and KIF20B. -
翻译后修饰
Phosphorylated upon DNA damage, probably by ATM or ATR. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 5300 Human
- Omim: 601052 Human
- SwissProt: Q13526 Human
- Unigene: 465849 Human
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别名
- DOD antibody
- DODO, Drosophila, homolog of antibody
- FLJ40239 antibody
see all
图片
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All lanes : Anti-Pin1 (phospho S16) antibody [EP1480Y] (ab62378) at 1/500 dilution
Lane 1 : HeLa cell lysate (untreated)
Lane 2 : HeLa cell lysate (treated with FBS + Calyculin A)
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat anti-Rabbit HRP conjugated at 1/2000 dilution
Predicted band size: 18 kDa
Observed band size: 18 kDa
The bottom image shows beta Tubulin.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab62378 尚未被引用在任何文献中。