重组Anti-Pin1抗体[S01-7G8] (ab317396)
![Western blot - Anti-Pin1 Antibody [S01-7G8] (ab317396)](https://www.abcam.cn/ps/products/317/ab317396/Images/ab317396-536527-anti-pin1-antibody-s01-7g8-western-blot-jurkat-brain-c6-chok1-hela-human-rat-chinese-hamster.jpg "Western blot - Anti-Pin1 Antibody [S01-7G8] (ab317396)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [S01-7G8] to Pin1
- Suitable for: WB, IHC-P
- Reacts with: Rat, Human, Chinese hamster
概述
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产品名称
Anti-Pin1抗体[S01-7G8]
参阅全部 Pin1 一抗 -
描述
兔单克隆抗体[S01-7G8] to Pin1 -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Rat, Human, Chinese hamster
预测可用于: Mouse
-
免疫原
Recombinant fragment corresponding to Mouse Pin1.
Database link: Q9QUR7 -
阳性对照
- WB: Jurkat, C6, CHO-K1 and HeLa cell lysate. Rat brain lysate. IHC-P: Human breast cancer tissue.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.4
Preservative: 0.01% Sodium azide
Constituents: 55.08% Water, 40% Glycerol (glycerin, glycerine), 0.98% Tris glycine, 0.88% Sodium chloride, 0.05% BSA -
Concentration information loading... -
纯度
Affinity purified -
克隆
单克隆 -
克隆编号
S01-7G8 -
同种型
IgG -
研究领域
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab317396于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/1000. Predicted molecular weight: 18 kDa.
|
|
| IHC-P |
1/20 - 1/50.
|
| 说明 |
|---|
|
WB
1/1000. Predicted molecular weight: 18 kDa. |
|
IHC-P
1/20 - 1/50. |
靶标
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功能
Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzing pSer/Thr-Pro cis/trans isomerizations. -
序列相似性
Contains 1 PpiC domain.
Contains 1 WW domain. -
结构域
The WW domain is required for the interaction with STIL and KIF20B. -
翻译后修饰
Phosphorylated upon DNA damage, probably by ATM or ATR. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 5300 Human
- Entrez Gene: 23988 Mouse
- Entrez Gene: 298696 Rat
- Omim: 601052 Human
- SwissProt: Q13526 Human
- SwissProt: Q9QUR7 Mouse
- Unigene: 465849 Human
- Unigene: 7906 Mouse
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别名
- DOD antibody
- DODO, Drosophila, homolog of antibody
- FLJ40239 antibody
see all
图片
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Western blot - Anti-Pin1 Antibody [S01-7G8] (ab317396)All lanes : Anti-Pin1 Antibody [S01-7G8] (ab317396) at 1/1000 dilution
Lane 1 : Jurkat cell lysate
Lane 2 : Rat brain lysate
Lane 3 : C6 cell lysate
Lane 4 : CHO-K1 cell lysate
Lane 5 : HeLa cell lysate
Predicted band size: 18 kDa -
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Pin1 Antibody [S01-7G8] (ab317396)](https://www.abcam.cn/ps/products/317/ab317396/Images/ab317396-536526-anti-pin1-antibody-s01-7g8-immunohistochemistry-breast-cancer-human.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Pin1 Antibody [S01-7G8] (ab317396)Immunohistochemistry of Pin1 in paraffin-embedded human breast cancer tissue using ab317396 at dilution 1/50.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab317396 尚未被引用在任何文献中。