重组Anti-PF4抗体[EPR7762] (ab129090)
![Western blot - Anti-PF4 antibody [EPR7762] (ab129090)](https://www.abcam.cn/ps/products/129/ab129090/Images/PF4-Primary-antibodies-ab129090-1.jpg "Western blot - Anti-PF4 antibody [EPR7762] (ab129090)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR7762] to PF4
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-PF4抗体[EPR7762]
参阅全部 PF4 一抗 -
描述
兔单克隆抗体[EPR7762] to PF4 -
宿主
Rabbit -
经测试应用
适用于: WBmore details
不适用于: ICC/IF,IHC-P or IP -
种属反应性
与反应: Human
预测可用于: Rat
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免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- Human spleen and Human platelet lysates
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Mouse: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
解离常数（KD）
KD = 2.00 x 10 -12 M Learn more about KD -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading... -
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EPR7762 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab129090于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/1000 - 1/10000. Detects a band of approximately 11 kDa (predicted molecular weight: 11 kDa).
|
| 说明 |
|---|
|
WB
1/1000 - 1/10000. Detects a band of approximately 11 kDa (predicted molecular weight: 11 kDa). |
应用说明
Is unsuitable for ICC/IF,IHC-P or IP.
靶标
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功能
Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form. -
序列相似性
Belongs to the intercrine alpha (chemokine CxC) family. -
翻译后修饰
Binds non-covalently to a proteoglycan molecule. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 5196 Human
- Entrez Gene: 360918 Rat
- Omim: 173460 Human
- SwissProt: P02776 Human
- SwissProt: P06765 Rat
- Unigene: 81564 Human
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别名
- C-X-C motif chemokine 4 antibody
- Chemokine (C X C motif) ligand 4 antibody
- Chemokine (CXC motif) ligand 4 antibody
see all
图片
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Western blot - Anti-PF4 antibody [EPR7762] (ab129090)All lanes : Anti-PF4 antibody [EPR7762] (ab129090) at 1/1000 dilution
Lane 1 : Human spleen lysate
Lane 2 : Human platelet lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 11 kDa
Observed band size: 11 kDa -
![OI-RD Scanning - Anti-PF4 antibody [EPR7762] (ab129090)](https://www.abcam.cn/ps/products/129/ab129090/Images/PF4-Primary-antibodies-ab129090-2.jpg)
OI-RD Scanning - Anti-PF4 antibody [EPR7762] (ab129090) -
![Anti-PF4 antibody [EPR7762] (ab129090)](https://www.abcam.cn/ps/products/129/ab129090/Images/ab129090-3-benefits-of-recombinant-antibodies.png)
Anti-PF4 antibody [EPR7762] (ab129090)
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab129090 被引用在 1 文献中.
- Liu S et al. HOXA9 inhibitors promote microcirculation of coronary arteries in rats via downregulating E-selectin/VCAM-1. Exp Ther Med 22:871 (2021). PubMed: 34194549