Anti-Peroxiredoxin 1/PAG抗体(ab109766)
Key features and details
- Goat polyclonal to Peroxiredoxin 1/PAG
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-Peroxiredoxin 1/PAG抗体
参阅全部 Peroxiredoxin 1/PAG 一抗 -
描述
山羊多克隆抗体to Peroxiredoxin 1/PAG -
宿主
Goat -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Cow, Cynomolgus monkey, Chinese hamster
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免疫原
Synthetic peptide corresponding to Human Peroxiredoxin 1/PAG aa 100-200 (internal sequence).
Database link: NP_859048.1 -
阳性对照
- IHC-P: placenta or thyroid tissue. WB: HepG2, HEK293 or A431 cell lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab109766于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 0.01 - 0.03 µg/ml. Detects a band of approximately 23-24 kDa (predicted molecular weight: 22 kDa).
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| IHC-P |
Use a concentration of 2.5 µg/ml.
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| 说明 |
|---|
|
WB
Use a concentration of 0.01 - 0.03 µg/ml. Detects a band of approximately 23-24 kDa (predicted molecular weight: 22 kDa). |
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IHC-P
Use a concentration of 2.5 µg/ml. |
靶标
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功能
Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation. -
序列相似性
Belongs to the ahpC/TSA family.
Contains 1 thioredoxin domain. -
翻译后修饰
Phosphorylated on Thr-90 during the M-phase, which leads to a more than 80% decrease in enzymatic activity. -
细胞定位
Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. - Information by UniProt
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数据库链接
- Entrez Gene: 281997 Cow
- Entrez Gene: 5052 Human
- Entrez Gene: 18477 Mouse
- Entrez Gene: 117254 Rat
- Omim: 176763 Human
- SwissProt: Q9JKY1 Chinese hamster
- SwissProt: Q5E947 Cow
- SwissProt: Q06830 Human
see all -
别名
- Heme binding 23 kDa protein antibody
- MSP23 antibody
- Natural killer cell-enhancing factor A antibody
see all
图片
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Western blot - Anti-Peroxiredoxin 1/PAG antibody (ab109766)Anti-Peroxiredoxin 1/PAG antibody (ab109766) at 0.01 µg/ml (incubation time: 1 hour) + HepG2 lysate in RIPA buffer at 35 µg
Developed using the ECL technique.
Predicted band size: 22 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Peroxiredoxin 1/PAG antibody (ab109766)ab109766 at 2.5µg/ml staining Peroxiredoxin 1/PAG in formalin-fixed, paraffin-embedded Human placenta tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Peroxiredoxin 1/PAG antibody (ab109766)ab109766 at 2.5µg/ml staining Peroxiredoxin 1/PAG in formalin-fixed, paraffin-embedded Human thyroid tissue.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab109766 尚未被引用在任何文献中。