Anti-Perilipin A+B抗体(ab3527)
Key features and details
- Rabbit polyclonal to Perilipin A+B
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
概述
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产品名称
Anti-Perilipin A+B抗体 -
描述
兔多克隆抗体to Perilipin A+B -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse -
免疫原
Synthetic peptide corresponding to Rat Perilipin A+B aa 1-100 (N terminal).
Database link: P43884 -
阳性对照
- WB: 3T3-L1 cell extract
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.05% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
纯度
IgG fraction -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/1000.
|
| 说明 |
|---|
|
WB
1/1000. |
靶标
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相关性
Perilipin is an intracellular neutral lipid droplet protein that is hormonally regulated. This protein is localized exclusively to the surface of lipid droplets. In response to lypotic stimuli, perilipin is phosphorylated by protein kinase A. Once activated, perilipin has inhibitory affects upon hormone-sensitive lipase (HSL), a protein that mediates the hydrolysis of triacylglycerol, the major form of stored energy in the body. Perilipin expression is limited to adipocytes and steroidogenic cells. There are currently two known isoforms, Perilipin A and B. Both of these proteins are encoded by a single-copy gene and are the result of differential splicing events. -
细胞定位
Lipid droplet -
数据库链接
- Entrez Gene: 103968 Mouse
- SwissProt: Q8CGN5 Mouse
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别名
- Lipid droplet associated protein antibody
- PERIA antibody
- PERIB antibody
see all
图片
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Western blot - Anti-Perilipin A+B antibody (ab3527)Anti-Perilipin A+B antibody (ab3527) + Cell extracts prepared from 3T3-L1 cells
Western blot detection of perilipin A and B in 3T3-L1 cell extract using ab3527.
数据表及文件
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Datasheet download
文献 (3)
ab3527 被引用在 3 文献中.
- Zheng N et al. Vancomycin pretreatment attenuates acetaminophen-induced liver injury through 2-hydroxybutyric acid. J Pharm Anal 10:560-570 (2020). PubMed: 33425450
- Matushansky I et al. A developmental model of sarcomagenesis defines a differentiation-based classification for liposarcomas. Am J Pathol 172:1069-80 (2008). WB ; Human . PubMed: 18310505
- Fernández-Veledo S et al. Hyperinsulinemia induces insulin resistance on glucose and lipid metabolism in a human adipocytic cell line: paracrine interaction with myocytes. J Clin Endocrinol Metab 93:2866-76 (2008). PubMed: 18430774
