JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB259772

重组Anti-Peptide YY/PYY抗体[EPR21011-57] - BSA and Azide free (Detector)

Anti-Peptide YY/PYY antibody [EPR21011-57] - BSA and Azide free (Detector)

Be the first to review this product! Submit a review

|

(0 Publication)

Rabbit Recombinant Monoclonal Peptide YY/PYY antibody. Carrier free. Suitable for sELISA and reacts with Human samples.

查看别名

Peptide YY, PYY, PYY-I, Peptide tyrosine tyrosine

1 Images
Sandwich ELISA - Anti-Peptide YY/PYY antibody [EPR21011-57] - BSA and Azide free (Detector) (AB259772)
  • sELISA

Supplier Data

Sandwich ELISA - Anti-Peptide YY/PYY antibody [EPR21011-57] - BSA and Azide free (Detector) (AB259772)

Representative standard curve from corresponding SimpleStep ELISA® Kit (ab255727).

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EPR21011-57

亚型

IgG

不含载体蛋白

Yes

反应种属

Human

应用

sELISA

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

style
left-column

搭配使用产品

Assay Kits

AB255727

Human PYY ELISA Kit

Recombinant|SimpleStep

Sandwich ELISA - Human PYY ELISA Kit (AB255727)

  • 0
  • 0
Sample Prep & Detection Kits

AB102918

PE / R-Phycoerythrin Conjugation Kit - Lightning-Link®

Flow Cytometry - PE / R-Phycoerythrin Conjugation Kit - Lightning-Link® (AB102918)

  • 5
  • 2
Sample Prep & Detection Kits

AB270709

5’ Feature Barcode Antibody Conjugation Kit - Lightning-Link® - Oligos 21-30

Schematic Diagram - 5’ Feature Barcode Antibody Conjugation Kit - Lightning-Link® - Oligos 21-30 (AB270709)

  • 0
  • 0
Primary Antibodies

AB242932

Anti-S100A9 antibody [EPR20066-233] - BSA and Azide free (Detector)

RabMAb|Recombinant

Sandwich ELISA - Anti-S100A9 antibody [EPR20066-233] - BSA and Azide free (Detector) (AB242932)

  • 0
  • 0
Primary Antibodies

AB244938

Anti-TREM2 antibody [EPR20243-269] - BSA and Azide free (Detector)

RabMAb|Recombinant

Sandwich ELISA - Anti-TREM2 antibody [EPR20243-269] - BSA and Azide free (Detector) (AB244938)

  • 0
  • 0
Primary Antibodies

AB244722

Anti-IL-20 antibody [EPR20756-1] - BSA and Azide free (Capture)

RabMAb|Recombinant

Sandwich ELISA - Anti-IL-20 antibody [EPR20756-1] - BSA and Azide free (Capture) (AB244722)

  • 0
  • 0
Primary Antibodies

AB259562

Anti-CTGF antibody [EPR20728-214] - BSA and Azide free (Detector)

RabMAb|Recombinant

Sandwich ELISA - Anti-CTGF antibody [EPR20728-214] - BSA and Azide free (Detector) (AB259562)

  • 0
  • 0
style
left-column

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "sELISA-species-checked": "guaranteed", "sELISA-species-dilution-info": "", "sELISA-species-notes": "<p></p>" } } }
style
left-column

产品详情

ab259772 is a BSA and Azide Free antibody supplied in an unconjugated format and it is suitable for sandwich ELISAs to quantify Human PYY. The recommended pair for sandwich ELISA is:
Capture: ab259771, Human PYY Capture Antibody (unconjugated)
Detector: ab259772, Human PYY Detector Antibody (unconjugated)
The reference range value is 15.63 - 1000 pg/ml.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Sandwich ELISA
The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Please note that the range provided for this antibody is only an estimation based on the performance of the product using the recommended antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody in your assay.

style
left-column

性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein A
存储溶液
Constituents: PBS
运输条件
Blue Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
+4°C
style
left-column

补充信息

This supplementary information is collated from multiple sources and compiled automatically.

Peptide YY (PYY) also known as PYY1 or PYY3-36 is a 36-amino acid peptide hormone with a molecular weight of approximately 4 kDa. Expressed primarily in the L-cells of the ileum and colon PYY is released into the bloodstream postprandially. This hormone serves as an important messenger in appetite control and energy homeostasis. Peptide YY reduces gastric motility and increases water and electrolyte absorption in the colon playing an integral role in digestion and nutrient absorption processes.
Biological function summary

The hormone influences several physiological functions beyond its mechanical roles. Peptide YY hormone function includes inhibiting appetite through interactions with the neuropeptide Y (NPY) receptors in the brain's hypothalamus. It acts together with similar peptides including pancreatic polypeptide (PP) and neuropeptide Y (NPY) establishing a complex regulatory system that governs energy balance and food intake. PYY contributes to short-term and long-term body weight management linking gut to brain signals.

Pathways

Peptide YY hormone function integrates into the gut-brain axis and the neuroendocrine system. It engages mainly in the regulation of the Y2 receptor pathway interacting with proteins like the ghrelin receptor and insulin pathways. Moreover PYY can influence the feeding pathway by modulating the arcuate nucleus neurons establishing connections with the melanocortin system and agouti-related peptide (AgRP). This integration importantly contributes to satiety and appetite modulation.

Peptide YY is linked to obesity and irritable bowel syndrome (IBS). Altered levels of PYY associate with increased risk of obesity due to dysregulated appetite signals. Disorders like IBS relate to the imbalance of functional gut hormones including PYY which impacts bowel motility and gastrointestinal comfort. Other proteins such as ghrelin and leptin participate in these pathways providing insight into potential therapeutic targets for these conditions.
style
left-column
style
left-column

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

靶点信息

This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.
See full target information PYY
style
left-column
style
left-column
style
right-column

Abcam Product Promise

我们致力于为您的研究提供高质量的试剂，为您科研的每一步提供支持。若我们的产品未能达到预期性能，我们向您提供 Abcam Product Promise 保障。
详情请参阅我们的条款与条件。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com