Anti-Pellino 1抗体(ab13812)
Key features and details
- Rabbit polyclonal to Pellino 1
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
概述
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产品名称
Anti-Pellino 1抗体
参阅全部 Pellino 1 一抗 -
描述
兔多克隆抗体to Pellino 1 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse, Human
预测可用于: Rat, Xenopus laevis
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免疫原
Synthetic peptide:
SQSNSDTQSV QSTIS
conjugated to KLH, corresponding to amino acids 121-135 of Human Pellino 1 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Preservative: 0.05% Sodium azide
Constituents: PBS, 0.05% BSA -
Concentration information loading... -
纯度
Protein G purified -
纯化说明
This antibody is affinity purified. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab13812于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | (2) |
1/500 - 1/1000. Predicted molecular weight: 46 kDa.
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| 说明 |
|---|
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WB
1/500 - 1/1000. Predicted molecular weight: 46 kDa. |
靶标
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功能
Scaffold protein involved in the IL-1 signaling pathway via its interaction with the complex containing IRAK kinases and TRAF6. Required for NF-kappa-B activation and IL-8 gene expression in response to IL-1. -
序列相似性
Belongs to the pellino family. - Information by UniProt
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数据库链接
- Entrez Gene: 57162 Human
- Entrez Gene: 67245 Mouse
- Entrez Gene: 305549 Rat
- Entrez Gene: 443954 Xenopus laevis
- Omim: 614797 Human
- SwissProt: Q96FA3 Human
- SwissProt: Q8C669 Mouse
- Unigene: 727530 Human
see all -
别名
- E3 ubiquitin-protein ligase pellino homolog 1 antibody
- PELI1 antibody
- PELI1_HUMAN antibody
see all
图片
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Western blot - Anti-Pellino 1 antibody (ab13812)All lanes : Anti-Pellino 1 antibody (ab13812) at 1/1000 dilution
Lane 1 : Lysates prepared from human Ramos cell line
Lane 2 : Lysates prepared from mouse Raw cell line
Predicted band size: 46 kDa
Western blot analysis of Pellino1 in human Ramos cell lysate (A) and mouse Raw cell lysate (B) using ab13812 at 1/1000
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab13812 被引用在 4 文献中.
- Thirunavukkarasu M et al. Disruption of VEGF Mediated Flk-1 Signaling Leads to a Gradual Loss of Vessel Health and Cardiac Function During Myocardial Infarction: Potential Therapy With Pellino-1. J Am Heart Assoc 7:e007601 (2018). PubMed: 30371196
- Rednam CK et al. Increased survivability of ischemic skin flap tissue in Flk-1+/- mice by Pellino-1 intervention. Microcirculation 24:N/A (2017). PubMed: 28177171
- Ma X et al. Interaction of the oncogenic miR-21 microRNA and the p53 tumor suppressor pathway. Carcinogenesis 34:1216-23 (2013). Mouse . PubMed: 23385064
- Kinsella S et al. Bid Promotes K63-Linked Polyubiquitination of Tumor Necrosis Factor Receptor Associated Factor 6 (TRAF6) and Sensitizes to Mutant SOD1-Induced Proinflammatory Signaling in Microglia. eNeuro 3:N/A (0). PubMed: 27257617