PE/DyLight™ 594 Anti-CD19抗体[4G7] (ab178449)
Key features and details
- PE/DyLight™ 594 Mouse monoclonal [4G7] to CD19
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: PE/DyLight™ 594
- Isotype: IgG1
概述
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产品名称
PE/DyLight™ 594 Anti-CD19抗体[4G7]
参阅全部 CD19 一抗 -
描述
PE/DyLight™ 594小鼠单克隆抗体[4G7] to CD19 -
宿主
Mouse -
偶联物
PE/DyLight™ 594 -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Human -
免疫原
Tissue, cells or virus corresponding to Human CD19. Human CCL (chronic lymphocytic leukemia) cells
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. Do Not Freeze. Store In the Dark. -
存储溶液
pH: 7.4
Preservative: 0.1% Sodium azide
Constituents: 99% PBS, 0.2% BSA
BSA is high-grade and protease free. -
Concentration information loading...
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纯度
Size exclusion -
纯化说明
The purified antibody is conjugated with tandem dye PE-DyLight™594 under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. -
克隆
单克隆 -
克隆编号
4G7 -
同种型
IgG1 -
研究领域
相关产品
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Alternative Versions
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Related Products
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab178449于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
Flow Cyt |
Use 4µl for 106 cells.
or per 100 µl of whole blood |
说明 |
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Flow Cyt
Use 4µl for 106 cells. or per 100 µl of whole blood |
靶标
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功能
Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. -
疾病相关
Defects in CD19 are the cause of immunodeficiency common variable type 3 (CVID3) [MIM:613493]; also called antibody deficiency due to CD19 defect. CVID3 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low. -
序列相似性
Contains 2 Ig-like C2-type (immunoglobulin-like) domains. -
翻译后修饰
Phosphorylated on serine and threonine upon DNA damage, probably by ATM or ATR. Phosphorylated on tyrosine following B-cell activation. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 930 Human
- Omim: 107265 Human
- SwissProt: P15391 Human
- Unigene: 652262 Human
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别名
- Antibody deficiency due to defect in CD19 antibody
- Antibody deficiency due to defect in CD19, included antibody
- AW495831 antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (0)
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