PE/Cy5® Anti-CD90 / Thy1抗体[G7] (ab25272)
![Flow Cytometry - PE/Cy5® Anti-CD90 / Thy1 antibody [G7] (ab25272)](https://www.abcam.cn/ps/products/25/ab25272/Images/ab25272-272339-anti-cd90-thy1-antibody-g7-pe-cy5-flow-cytometry.jpg "Flow Cytometry - PE/Cy5® Anti-CD90 / Thy1 antibody [G7] (ab25272)")
Key features and details
- PE/Cy5® Rat monoclonal [G7] to CD90 / Thy1
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: PE/Cy5®. Ex: 496nm, Em: 670nm
- Isotype: IgG2c
概述
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产品名称
PE/Cy5® Anti-CD90 / Thy1抗体[G7]
参阅全部 CD90 / Thy1 一抗 -
描述
PE/Cy5®大鼠单克隆抗体[G7] to CD90 / Thy1 -
宿主
Rat -
偶联物
PE/Cy5®. Ex: 496nm, Em: 670nm -
特异性
ab25272 is specific for Thy-1.1 and Thy-1.2 alloantigens (Thy-1 epitope region A). -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Mouse -
免疫原
Tissue, cells or virus corresponding to CD90/ Thy1. Mouse T cell hybridoma C6/G8
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常规说明
ab25272 stimulates T-cell proliferation and IL-2 secretion, via signalling through the T-cell receptor/CD3 complex. ab25272 has also been reported to promote apoptosis of thymocytes and CTL clones, and to mediate adhesion of thymocytes to thymic stroma.
This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5, 268, 486 and related patents. Cy® and CyDye® are trademarks of Cytiva.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. Store In the Dark. -
存储溶液
pH: 7.1
Preservative: 0.09% Sodium azide
Constituents: PBS, 0.2% Gelatin, 16% Sucrose
Stabilising agent. -
Concentration information loading... -
纯度
Affinity purified -
Primary antibody说明
ab25272 stimulates T-cell proliferation and IL-2 secretion, via signalling through the T-cell receptor/CD3 complex. ab25272 has also been reported to promote apoptosis of thymocytes and CTL clones, and to mediate adhesion of thymocytes to thymic stroma. -
克隆
单克隆 -
克隆编号
G7 -
同种型
IgG2c -
轻链类型
kappa -
研究领域
相关产品
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Alternative Versions
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab25272于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt |
Use 0.2µg for 106 cells.
|
| 说明 |
|---|
|
Flow Cyt
Use 0.2µg for 106 cells. |
靶标
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功能
May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. -
序列相似性
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 21838 Mouse
- SwissProt: P01831 Mouse
- Unigene: 3951 Mouse
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别名
- CD7 antibody
- CD90 antibody
- CD90 antigen antibody
see all
图片
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Flow Cytometry - PE/Cy5® Anti-CD90 / Thy1 antibody [G7] (ab25272)
Flow Cytometry analysis of C57BL/6 mouse splenocytes stained with Anti-CD90 / Thy1 antibody [G7] (PE/Cy5) ab25272 (1 µg/106cells) and Rat Anti-Mouse CD3-epsilon-PE.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (8)
ab25272 被引用在 8 文献中.
- Yang C et al. microRNA-143-3p regulates odontogenic differentiation of human dental pulp stem cells through regulation of the osteoprotegerin-RANK ligand pathway by targeting RANK. Exp Physiol 105:876-885 (2020). PubMed: 32052500
- Hu J et al. Effects of menstrual blood-derived stem cells on endometrial injury repair. Mol Med Rep 19:813-820 (2019). PubMed: 30569163
- Hueber AO et al. Thy-1 triggers mouse thymocyte apoptosis through a bcl-2-resistant mechanism. J Exp Med 179:785-96 (1994). PubMed: 7906706
- Ucker DS et al. Activation-driven T cell death. II. Quantitative differences alone distinguish stimuli triggering nontransformed T cell proliferation or death. J Immunol 149:1583-92 (1992). PubMed: 1380534
- He HT et al. Thy-1 supports adhesion of mouse thymocytes to thymic epithelial cells through a Ca2(+)-independent mechanism. J Exp Med 173:515-8 (1991). PubMed: 1671083
- Sugiyama E et al. Selection of T cell receptor expression mutants through the functionally linked Ly-6A. Cell Immunol 130:271-80 (1990). PubMed: 1976441
- Tentori L et al. Proliferation and production of IL-2 and B cell stimulatory factor 1/IL-4 in early fetal thymocytes by activation through Thy-1 and CD3. J Immunol 140:1089-94 (1988). PubMed: 2893823
- Gunter KC et al. T cell-activating properties of an anti-Thy-1 monoclonal antibody. Possible analogy to OKT3/Leu-4. J Exp Med 159:716-30 (1984). PubMed: 6142077