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Signal Transduction Cytoskeleton / ECM Cell Adhesion Integrins Alpha

PE/Cy5® Anti-CD11c抗体[N418] (ab272256)

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Flow Cytometry - PE/Cy5® Anti-CD11c antibody [N418] (ab272256)

    Key features and details

    • PE/Cy5® Armenian hamster monoclonal [N418] to CD11c
    • Suitable for: Flow Cyt
    • Reacts with: Mouse
    • Conjugation: PE/Cy5®. Ex: 496nm, Em: 670nm
    • Isotype: IgG

    Conjugates logo Related conjugates and formulations

    Alexa Fluor® 488 Alexa Fluor® 647 APC APC/Cy7® Biotin Carrier Free Carrier Free FITC PE PE/Cy7® PerCP/Cy5.5® Unconjugated violetFluor™ 450

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    概述

    • 产品名称

      PE/Cy5® Anti-CD11c抗体[N418]
      参阅全部 CD11c 一抗
    • 描述

      PE/Cy5®亚美尼亚仓鼠单克隆抗体[N418] to CD11c
    • 宿主

      Armenian hamster
    • 偶联物

      PE/Cy5®. Ex: 496nm, Em: 670nm
    • 经测试应用

      适用于: Flow Cytmore details
    • 种属反应性

      与反应: Mouse
    • 免疫原

      Tissue, cells or virus corresponding to Mouse CD11c.

    • 阳性对照

      • Flow Cyt: C57Bl/6 splenocytes.
    • 常规说明

      This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5, 268, 486 and related patents. Cy® and CyDye® are trademarks of Cytiva.

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    性能

    • 形式

      Liquid
    • 存放说明

      Shipped at 4°C. Store at +4°C. Store In the Dark.
    • 存储溶液

      pH: 7.20
      Preservative: 0.09% Sodium azide
      Constituents: 0.12% Monobasic dihydrogen sodium phosphate, 0.87% Sodium chloride, 0.1% Gelatin
    • Concentration information loading...
    • 纯度

      Affinity purified
    • 纯化说明

      Purified from tissue culture supernatant.
    • 克隆

      单克隆
    • 克隆编号

      N418
    • 同种型

      IgG
    • 研究领域

      • Signal Transduction
      • Cytoskeleton / ECM
      • Cell Adhesion
      • Integrins
      • Alpha
      • Immunology
      • Cell Type Markers
      • CD
      • Adhesion
      • Stem Cells
      • Hematopoietic Progenitors
      • Lymphoid
      • T Lymphocytic Lineage
      • Stem Cells
      • Hematopoietic Progenitors
      • Myeloid
      • Dendritic Cell Lineage
      • Stem Cells
      • Hematopoietic Progenitors
      • Myeloid
      • Monocytic Lineage

    应用

    The Abpromise guarantee

    Abpromise™承诺保证使用ab272256于以下的经测试应用

    “应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。

    应用 Ab评论 说明
    Flow Cyt
    Use at an assay dependent concentration.
    说明
    Flow Cyt
    Use at an assay dependent concentration.

    靶标

    • 功能

      Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
    • 组织特异性

      Predominantly expressed in monocytes and granulocytes.
    • 序列相似性

      Belongs to the integrin alpha chain family.
      Contains 7 FG-GAP repeats.
      Contains 1 VWFA domain.
    • 结构域

      The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
    • 细胞定位

      Membrane.
    • Target information above from: UniProt accession P20702 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • 数据库链接

      • Entrez Gene: 16411 Mouse
      • SwissProt: Q9QXH4 Mouse
      • Unigene: 22378 Mouse
      • 别名

        • 95 alpha chain antibody
        • 95 antibody
        • CD 11c antibody
        • CD11 antigen like family member C antibody
        • CD11 antigen-like family member C antibody
        • CD11c antibody
        • CD11c antigen antibody
        • Complement component 3 receptor 4 subunit antibody
        • CR4 antibody
        • Integrin alpha X antibody
        • Integrin alpha X chain antibody
        • Integrin alpha-X antibody
        • Integrin aX antibody
        • Integrin subunit alpha X antibody
        • integrin, alpha X (antigen CD11C (p150), alpha polypeptide) antibody
        • integrin, alpha X (complement component 3 receptor 4 subunit antibody
        • ITAX_HUMAN antibody
        • ITGAX antibody
        • LEU M5 alpha subunit antibody
        • Leu M5 antibody
        • Leukocyte adhesion glycoprotein p150 95 alpha chain antibody
        • Leukocyte adhesion glycoprotein p150 antibody
        • Leukocyte adhesion receptor p150 95 antibody
        • Leukocyte adhesion receptor p150 antibody
        • Leukocyte surface antigen p150 95 alpha subunit antibody
        • Leukocyte surface antigen p150 alpha subunit antibody
        • Myeloid membrane antigen alpha subunit antibody
        • p150 95 integrin alpha chain antibody
        • p150 antibody
        • p150/95 antibody
        • SLEB6 antibody
        see all

      图片

      • Flow Cytometry - PE/Cy5® Anti-CD11c antibody [N418] (ab272256)
        Flow Cytometry - PE/Cy5® Anti-CD11c antibody [N418] (ab272256)

        C57Bl/6 splenocytes were stained with APC Anti-Mouse MHC Class II and 0.25 ug ab272256 (right panel) or 0.25 ug PECyanine5 Armenian Hamster IgG (left panel).

      实验方案

      To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

      Click here to view the general protocols

      数据表及文件

      • Datasheet download

        Download

      文献 (0)

      发表研究结果有使用 ab272256?请让我们知道,以便我们可以引用本数据表中的参考文章。

      ab272256 尚未被引用在任何文献中。

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      Please use the links above to contact us or submit feedback about this product.

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      For licensing inquiries, please contact partnerships@abcam.com

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