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AB269329

PE Anti-Syndecan-1抗体[MI15]

PE Anti-Syndecan-1 antibody [MI15]

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(0 Publication)

Anti-Syndecan-1 antibody [MI15] conjugated to PE - suitable for flow cytometry, and reacts with human samples. Clone [MI15] is a mouse monoclonal antibody cited in 89 publications.

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查看别名

CD138, SDC, SDC1, Syndecan-1, SYND1

1 Images
Flow Cytometry - PE Anti-Syndecan-1 antibody [MI15] (AB269329)
  • Flow Cyt

Unknown

Flow Cytometry - PE Anti-Syndecan-1 antibody [MI15] (AB269329)

Surface staining of human peripheral blood labeling CD138 with ab269329.

不同偶联物与剂型 (2)

关键信息

宿主种属

Mouse

克隆

Monoclonal

克隆号

MI15

亚型

IgG1

轻链类型

kappa

偶联物

PE

激发波长/发射波长

Ex: 480;565nm, Em: 578nm

不含载体蛋白

No

反应种属

Human

应用

Flow Cyt

applications

免疫原

Cell preparation containing SDC1 protein. The exact immunogen used to generate this antibody is proprietary information.

P18827

特异性

<p>ab269329 recognizes an extracellular epitope of CD138&#46;</p>

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替代产品

Primary Antibodies

AB128936

Anti-Syndecan-1 antibody [EPR6454]

20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Syndecan-1 antibody [EPR6454] (AB128936)

  • 5
  • 7
Primary Antibodies

AB130405

Anti-Syndecan-1 antibody [SP152]

20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Syndecan-1 antibody [SP152] (AB130405)

  • 0
  • 0
Primary Antibodies

AB216458

Anti-Syndecan-1 antibody [EPR6454] - Low endotoxin, Azide free

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Syndecan-1 antibody [EPR6454] - Low endotoxin, Azide free (AB216458)

  • 0
  • 0
Primary Antibodies

AB226108

Anti-Syndecan-1 antibody [EPR6454] - BSA and Azide free

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Syndecan-1 antibody [EPR6454] - BSA and Azide free (AB226108)

  • 0
  • 0
Primary Antibodies

AB242394

Anti-Syndecan-1 antibody [SP152] - BSA and Azide free

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Syndecan-1 antibody [SP152] - BSA and Azide free (AB242394)

  • 5
  • 1
Primary Antibodies

AB34164

Anti-Syndecan-1 antibody [B-A38]

Flow Cytometry - Anti-Syndecan-1 antibody [B-A38] (AB34164)

  • 5
  • 10

搭配使用产品

Assay Kits

AB46506

Human Syndecan-1 ELISA Kit (CD138)

ELISA - Human Syndecan-1 ELISA Kit (CD138) (AB46506)

  • 0
  • 0
Primary Antibodies

AB196515

Alexa Fluor® 647 Anti-CD19 antibody [EPR5906]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Alexa Fluor® 647 Anti-CD19 antibody [EPR5906] (AB196515)

  • 5
  • 1
Primary Antibodies

AB200315

Alexa Fluor® 488 Anti-CD45 antibody [EP322Y]

RabMAb|Recombinant

Flow Cytometry (Intracellular) - Alexa Fluor® 488 Anti-CD45 antibody [EP322Y] (AB200315)

  • 0
  • 0
Primary Antibodies

AB310764

Alexa Fluor® 594 Anti-CD38 antibody [SP149] - C-terminal

RabMAb|Recombinant

  • 0
  • 0
Primary Antibodies

AB196147

Alexa Fluor® 647 Anti-CD4 antibody [EPR6855]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Alexa Fluor® 647 Anti-CD4 antibody [EPR6855] (AB196147)

  • 5
  • 1
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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "10 µL for 10^6 Cells", "FlowCyt-species-notes": "<p>Or 100 μL of whole blood.</p>" }, "Primates": { "FlowCyt-species-checked": "predicted", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "" } } }
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性能和储存信息

形式
Liquid
纯化工艺
Size-exclusion chromatography
纯化说明
The purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
存储溶液
pH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS
运输条件
Blue Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
+4°C
储存信息
Store in the dark
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

Syndecan-1 also known as CD138 is a transmembrane heparan sulfate proteoglycan with a molecular weight of approximately 30 to 80 kDa. The size variation arises from differences in its glycosaminoglycan chains. This protein resides predominantly on the surface of epithelial cells and plasma cells. Researchers commonly use the CD138 marker to identify these cells in biological samples. It plays a significant role in cell-cell and cell-matrix interactions acting as a co-receptor for a variety of growth factors cytokines and extracellular matrix proteins.
Biological function summary

Syndecan-1 participates in tissue repair inflammation and cell signaling ensuring epithelial integrity and communication. Syndecan-1 influences cell behavior by interacting with other components of the extracellular matrix and different membrane receptors. It is also involved in forming and regulating proteoglycan complexes at the cell surface. These complex interactions facilitate the modulation of cell proliferation migration and differentiation which are fundamental to maintaining tissue architecture and function.

Pathways

Syndecan-1 actively contributes to both the Wnt and FGF signaling pathways. Through its interaction with proteins such as miR-15 syndecan-1 modulates cellular responses essential for developmental processes and tissue homeostasis. The connection with these pathways allows syndecan-1 to integrate and relay extracellular signals impacting gene expression and cellular behavior. Its relationship with other proteins like A38 as a co-receptor emphasizes its role in finely tuning signaling cascades within cellular environments.

Syndecan-1 shows a connection to multiple myeloma and breast cancer. The overexpression of syndecan-1 in these conditions disrupts normal cellular functions and promotes tumorigenesis by aiding in the tumor cell's adhesion migration and invasion. Its interaction with proteins such as perCP further demonstrates its role in disease progression providing potential as a therapeutic target. These relationships make syndecan-1 an important focus for research in oncology and other fields of disease study.
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix (By similarity). Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed : 22660413). Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway (By similarity).
See full target information SDC1
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