PE Anti-Interferon gamma抗体[4S.B3] (ab178447)
Key features and details
- PE Mouse monoclonal [4S.B3] to Interferon gamma
- Suitable for: Flow Cyt (Intra)
- Reacts with: Human
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
Related conjugates and formulations
概述
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产品名称
PE Anti-Interferon gamma抗体[4S.B3]
参阅全部 Interferon gamma 一抗 -
描述
PE小鼠单克隆抗体[4S.B3] to Interferon gamma -
宿主
Mouse -
偶联物
PE. Ex: 488nm, Em: 575nm -
特异性
Binds both glycosylated and non-glycosylated protein. -
经测试应用
适用于: Flow Cyt (Intra)more details -
种属反应性
与反应: Human
预测可用于: Non human primates -
免疫原
Full length native protein (purified) corresponding to Human Interferon gamma. Interferon gamma derived from Human leukocytes.
Database link: P01579 -
阳性对照
- FLow Cyt (Intra):PHA-activated human peripheral blood cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. Do Not Freeze. Store In the Dark. -
存储溶液
pH: 7.4
Preservative: 0.1% Sodium azide
Constituents: 0.2% BSA, 99% PBS
BSA is high-grade and protease free. -
Concentration information loading...
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纯度
Size exclusion -
克隆
单克隆 -
克隆编号
4S.B3 -
同种型
IgG1 -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Recombinant Protein
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Related Products
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab178447于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
Flow Cyt (Intra) |
Use 10µl for 106 cells.
or 100 µl of whole blood. ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
说明 |
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Flow Cyt (Intra)
Use 10µl for 106 cells. or 100 µl of whole blood. ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
靶标
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功能
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. -
组织特异性
Released primarily from activated T lymphocytes. -
疾病相关
In Caucasians, genetic variation in IFNG is associated with the risk of aplastic anemia (AA) [MIM:609135]. AA is a rare disease in which the reduction of the circulating blood cells results from damage to the stem cell pool in bone marrow. In most patients, the stem cell lesion is caused by an autoimmune attack. T-lymphocytes, activated by an endogenous or exogenous, and most often unknown antigenic stimulus, secrete cytokines, including IFN-gamma, which would in turn be able to suppress hematopoiesis. -
序列相似性
Belongs to the type II (or gamma) interferon family. -
翻译后修饰
Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 3458 Human
- Omim: 147570 Human
- SwissProt: P01579 Human
- Unigene: 856 Human
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别名
- IF 1 antibody
- IFG antibody
- IFI antibody
see all
图片
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Intracellular Flow Cytometry analysis of PHA-activated human peripheral blood cells labeling Interferon gamma with Anti-Interferon gamma antibody [4S.B3] (Phycoerythrin) (ab178447).
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Intracellular Flow Cytometry analysis of Interferon gammaexpression in PHA-activated human PBMC with Anti-Interferon gamma antibody [4S.B3] (Phycoerythrin) (ab178447).
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab178447 尚未被引用在任何文献中。