PE Anti-ICAM1抗体[YN1/1.7.4] (ab25553)
![Flow Cytometry - PE Anti-ICAM1 antibody [YN1/1.7.4] (ab25553)](https://www.abcam.cn/ps/products/25/ab25553/Images/ab25553-272406-anti-icam1-antibody-yn1-174-phycoerythrin-flow-cytometry.jpg "Flow Cytometry - PE Anti-ICAM1 antibody [YN1/1.7.4] (ab25553)")
Key features and details
- PE Rat monoclonal [YN1/1.7.4] to ICAM1
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG2b
概述
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产品名称
PE Anti-ICAM1抗体[YN1/1.7.4]
参阅全部 ICAM1 一抗 -
描述
PE大鼠单克隆抗体[YN1/1.7.4] to ICAM1 -
宿主
Rat -
偶联物
PE. Ex: 488nm, Em: 575nm -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Mouse -
免疫原
Tissue, cells or virus corresponding to ICAM1. Mouse NS-1 cells
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. Store In the Dark. -
存储溶液
pH: 7.3
Preservative: 0.09% Sodium azide
Constituents: PBS, 16% Sucrose
Also contains a stabilizing agent. -
Concentration information loading... -
纯度
Affinity purified -
克隆
单克隆 -
克隆编号
YN1/1.7.4 -
同种型
IgG2b -
轻链类型
kappa -
研究领域
相关产品
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Alternative Versions
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab25553于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt | (1) |
Use 0.2µg for 106 cells.
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| 说明 |
|---|
|
Flow Cyt
Use 0.2µg for 106 cells. |
靶标
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功能
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. -
序列相似性
Belongs to the immunoglobulin superfamily. ICAM family.
Contains 5 Ig-like C2-type (immunoglobulin-like) domains. -
翻译后修饰
Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 15894 Mouse
- SwissProt: P13597 Mouse
- Unigene: 435508 Mouse
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别名
- Antigen identified by monoclonal antibody BB2 antibody
- BB 2 antibody
- BB2 antibody
see all
图片
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Flow Cytometry - PE Anti-ICAM1 antibody [YN1/1.7.4] (ab25553)
Flow cytometric analysis of C57BL/6 mouse splenocytes labelling ICAM1 with ab25553 at 0.1 μg/106 cells and labelling CD49b with a Rat Anti-Mouse CD49b-FITC antibody.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab25553 被引用在 4 文献中.
- Qin L et al. The roles of CD11/CD18 and ICAM-1 in acute Pseudomonas aeruginosa-induced pneumonia in mice. J Immunol 157:5016-21 (1996). PubMed: 8943409
- Welder CA et al. Inhibition of cell adhesion by microspheres coated with recombinant soluble intercellular adhesion molecule-1. J Immunol 150:2203-10 (1993). PubMed: 8095510
- Horley KJ et al. Molecular cloning of murine intercellular adhesion molecule (ICAM-1). EMBO J 8:2889-96 (1989). PubMed: 2573511
- Takei F Inhibition of mixed lymphocyte response by a rat monoclonal antibody to a novel murine lymphocyte activation antigen (MALA-2). J Immunol 134:1403-7 (1985). PubMed: 2981916