PE Anti-HLA G抗体[MEM-G/9] (ab24384)
Key features and details
- PE Mouse monoclonal [MEM-G/9] to HLA G
- Suitable for: Flow Cyt
- Reacts with: Recombinant fragment
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
Related conjugates and formulations
概述
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产品名称
PE Anti-HLA G抗体[MEM-G/9]
参阅全部 HLA G 一抗 -
描述
PE小鼠单克隆抗体[MEM-G/9] to HLA G -
宿主
Mouse -
偶联物
PE. Ex: 488nm, Em: 575nm -
特异性
The antibody reacts with native form of human HLA-G1 on the cell surface as well as with soluble HLA-G5 isoform in its beta2-microglobulin associated form. We have data to indicate that this antibody may not cross react with Mouse. However, this has not been conclusively tested and expression levels may vary in certain cell lines/tissues. -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Recombinant fragment -
免疫原
Recombinant full length protein (Human) refolded with beta2-microglobulin and peptide.
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常规说明
The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.4
Preservative: 0.097% Sodium azide
Constituents: PBS, 0.2% BSA -
Concentration information loading...
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纯度
Protein A purified -
克隆
单克隆 -
克隆编号
MEM-G/9 -
同种型
IgG1 -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab24384于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
Flow Cyt |
Use a concentration of 1 - 4 µg/ml.
Do not fix cells.ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
说明 |
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Flow Cyt
Use a concentration of 1 - 4 µg/ml. Do not fix cells.ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
靶标
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功能
Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T lymphocytes, macrophages and mononuclear cells. -
组织特异性
Expressed in trophoblasts. -
序列相似性
Belongs to the MHC class I family.
Contains 1 Ig-like C1-type (immunoglobulin-like) domain. -
细胞定位
Membrane. - Information by UniProt
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别名
- B2 microglobulin antibody
- DADB-15K14.8 antibody
- HLA 6.0 antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (12)
ab24384 被引用在 12 文献中.
- Hamilton I et al. Utilizing primary HLA-G+ extravillous trophoblasts and HLA-G+ EVT-like cell lines to study maternal-fetal interactions. STAR Protoc 4:102276 (2023). PubMed: 37178111
- Eikmans M et al. Primary Trophoblast Cultures: Characterization of HLA Profiles and Immune Cell Interactions. Front Immunol 13:814019 (2022). PubMed: 35634345
- Nikoo S et al. Culture density of menstrual blood-derived stromal/stem cells determines the quality of T cell responses: An experimental study. Int J Reprod Biomed 19:75-86 (2021). PubMed: 33554005
- Carré T et al. Selection of tumor-resistant variants following sustained natural killer cell-mediated immune stress. Oncol Rep 45:582-594 (2021). PubMed: 33416152
- Sheridan MA et al. Establishment and differentiation of long-term trophoblast organoid cultures from the human placenta. Nat Protoc 15:3441-3463 (2020). PubMed: 32908314