PE Anti-HLA DR + HLA DP抗体[MEM-136] (ab77134)
Key features and details
- PE Mouse monoclonal [MEM-136] to HLA DR + HLA DP
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
概述
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产品名称
PE Anti-HLA DR + HLA DP抗体[MEM-136]
参阅全部 HLA DR + HLA DP 一抗 -
描述
PE小鼠单克隆抗体[MEM-136] to HLA DR + HLA DP -
宿主
Mouse -
偶联物
PE. Ex: 488nm, Em: 575nm -
特异性
ab77134 recognizes a common epitope on the beta chain of human HLA-DR and HLA-DP. It reacts with alpha/beta dimer as well as with dissociated beta subunit. -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Human -
免疫原
Tissue, cells or virus corresponding to Human HLA DR + HLA DP. PHA-activated peripheral blood lymphocytes
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阳性对照
- human blood cells
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常规说明
Conjugates are made from highly purified antibodies (>95% by SDS-PAGE).
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.4
Preservative: 0.097% Sodium azide
Constituents: 0.2% BSA, 0.2% PBS
0.2% BSA (high-grade protease free) -
Concentration information loading... -
纯度
Size exclusion -
纯化说明
The protein A/G purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is then purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary. -
克隆
单克隆 -
克隆编号
MEM-136 -
同种型
IgG1 -
研究领域
相关产品
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Alternative Versions
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab77134于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt |
| 说明 |
|---|
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
靶标
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相关性
Human MHC class II antigens are transmembrane glycoproteins composed of an alpha (36 kDa) and a beta chain (27kDa) and are expressed primarily on antigen presenting cells. Human MHC class II genes are located in the HLA-D region that encodes at least 6 alpha and 10 beta chain genes. Three loci, DR, DQ and DP, encode the major products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells and therefore have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles. -
细胞定位
Cell Membrane; Single pass type I membrane protein -
数据库链接
- Entrez Gene: 3115 Human
- Entrez Gene: 3122 Human
- Entrez Gene: 3123 Human
- Entrez Gene: 3125 Human
- Entrez Gene: 3126 Human
- Entrez Gene: 3127 Human
- Entrez Gene: 972 Human
- Omim: 142858 Human
see all -
别名
- HLA DP antibody
- HLA DR antibody
- MHC Class II antibody
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab77134 尚未被引用在任何文献中。