AB134381

PE Anti-CD40抗体[5C3]

Name: PE Anti-CD40抗体[5C3] (ab134381)| Abcam中文官网
Brand: Abcam Limited
SKU: AB134381
Price: 1633 CNY
Availability: InStock

PE Anti-CD40 antibody [5C3]

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(1 Publication)

Anti-CD40 antibody [5C3] conjugated to PE - suitable for flow cytometry, and reacts with human samples. Clone [5C3] is a mouse monoclonal antibody and one of the most commonly used clones for flow cytometry.

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查看别名

CD40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor, CDw40

1 Images

Flow Cytometry - PE Anti-CD40 antibody [5C3] (AB134381)

Flow Cyt

Unknown

Flow Cytometry - PE Anti-CD40 antibody [5C3] (AB134381)

Flow cytometry analysis of normal Human peripheral blood cells with Mouse IgG1 K Isotype Control PE (blue histogram) or ab134381 at 5 µl (0.015 µg)/ test (purple histogram). Cells in the lymphocyte gate were used for analysis.

不同偶联物与剂型 (1)

519 FITC

FITC Anti-CD40 antibody [5C3]

关键信息

宿主种属

Mouse

克隆

Monoclonal

克隆号

5C3

亚型

IgG1

轻链类型

kappa

偶联物

激发波长/发射波长

Ex: 480;565nm, Em: 578nm

不含载体蛋白

反应种属

Human

应用

Flow Cyt

applications

免疫原

Recombinant Full Length Protein corresponding to Human CD40.

P25942

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "5 µL for 10^6 Cells", "FlowCyt-species-notes": "<p></p>" } } }

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产品详情

The 5C3 clone is reported to be used for activation of B cells in in vitro functional assays.

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Protein G

存储溶液

pH: 7.2 Preservative: 0.09% Sodium azide Constituents: PBS, 0.2% BSA

运输条件

Blue Ice

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

Receptor for TNFSF5/CD40LG (PubMed : 31331973). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).

See full target information CD40

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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

JCI insight 9: PubMed38227377

2024

C3aR-initiated signaling is a critical mechanism of podocyte injury in membranous nephropathy.

Applications

Unspecified application

Species

Unspecified reactive species

Qi Zhang,Sofia Bin,Kelly Budge,Astgik Petrosyan,Valentina Villani,Paola Aguiari,Coralien Vink,Jack Wetzels,Hasmik Soloyan,Gaetano La Manna,Manuel Alfredo Podestà,Paolo Molinari,Sargis Sedrakyan,Kevin V Lemley,Roger E De Filippo,Laura Perin,Paolo Cravedi,Stefano Da Sacco

View all publications

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Abcam Product Promise

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详情请参阅我们的条款与条件。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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PE Anti-CD40抗体[5C3]