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AB18282

PE Anti-CD4抗体[MEM-241]

PE Anti-CD4 antibody [MEM-241]

2

(6 Reviews)

|

(5 Publications)

Mouse Monoclonal CD4 antibody - conjugated to PE. Suitable for Flow Cyt and reacts with Human samples. Cited in 5 publications. Immunogen corresponding to Recombinant Fragment Protein within Human CD4.

查看别名

CD4, T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3

1 Images
Flow Cytometry - PE Anti-CD4 antibody [MEM-241] (AB18282)
  • Flow Cyt

Unknown

Flow Cytometry - PE Anti-CD4 antibody [MEM-241] (AB18282)

ab18282 staining CD4 in human T cells by Flow Cytometry .

关键信息

宿主种属

Mouse

克隆

Monoclonal

克隆号

MEM-241

亚型

IgG1

轻链类型

kappa

偶联物

PE

激发波长/发射波长

Ex: 480;565nm, Em: 578nm

不含载体蛋白

No

反应种属

Human

应用

Flow Cyt

applications

免疫原

Recombinant Fragment Protein within Human CD4. The exact immunogen used to generate this antibody is proprietary information.

P01730

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p>Use 5-20μl for 100μl whole human blood cells.</p><p><a href='/products/primary-antibodies/pe-mouse-igg1-b11-6-isotype-control-ab91357'>ab91357</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>" } } }

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为什么推荐这个?

我们推荐这个产品,因为它经常被用于相同的实验或相关的研究。

我们建议您务必查阅产品说明书,以确认其是否符合您的实验需求;若有疑问,也可联系我们的技术团队获取协助。

产品详情

The purified antibody is conjugated with R-Phycoerythrin (R-PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.

性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein G
存储溶液
pH: 7.4 Preservative: 0.097% Sodium azide Constituents: BSA, PBS
运输条件
Blue Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
+4°C
储存信息
Do Not Freeze

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

靶点信息

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule : peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages.. (Microbial infection) Primary receptor for human immunodeficiency virus-1 (HIV-1) (PubMed : 12089508, PubMed : 16331979, PubMed : 2214026, PubMed : 9641677). Down-regulated by HIV-1 Vpu (PubMed : 17346169). Acts as a receptor for Human Herpes virus 7/HHV-7 (PubMed : 7909607).
See full target information CD4

文献 (5)

Recent publications for all applications. Explore the full list and refine your search

Cell death & disease 13:160 PubMed35181676

2022

HOXA-AS2 contributes to regulatory T cell proliferation and immune tolerance in glioma through the miR-302a/KDM2A/JAG1 axis.

Applications

Unspecified application

Species

Unspecified reactive species

Chuanhong Zhong,Bei Tao,Xianglong Li,Wei Xiang,Lilei Peng,Tangming Peng,Ligang Chen,Xiangguo Xia,Jian You,Xiaobo Yang

Micromachines 11: PubMed32630535

2020

Improved Enumeration of Weakly Fluorescent CD4+ T-lymphocytes by Confining Cells in a Spinning Sample Cartridge with a Helical Minichannel.

Applications

Unspecified application

Species

Unspecified reactive species

Subin Kim,Jakir Hossain Imran,Mohiuddin Khan Shourav,Jung Kyung Kim

Lab on a chip 19:589-597 PubMed30648711

2019

Two-level submicron high porosity membranes (2LHPM) for the capture and release of white blood cells (WBCs).

Applications

Unspecified application

Species

Unspecified reactive species

Javier Alejandro Hernández-Castro,Kebin Li,Jamal Daoud,David Juncker,Teodor Veres

Traffic (Copenhagen, Denmark) 16:1330-41 PubMed26771955

2015

Munc18-2 is required for Syntaxin 11 Localization on the Plasma Membrane in Cytotoxic T-Lymphocytes.

Applications

Unspecified application

Species

Unspecified reactive species

Nele M G Dieckmann,Yvonne Hackmann,Maurizio Aricò,Gillian M Griffiths

Cell journal 13:281-9 PubMed23507624

2012

The Effects of Isoproterenol and Propranolol on Cytokine Profile Secretion by Cultured Tumor-infiltrating Lymphocytes Derived from Colorectal Cancer Patients.

Applications

Unspecified application

Species

Unspecified reactive species

Shahram Seyedi,Alireza Andalib,Abbas Rezaei,Seyed Mohsen Hosseini,Seyed Reza Mohebbi,Mohammad Reza Zali,Mohamad Vafai,Roubik Behboo,Seyed Abbas Tabatabaei,Shahram Shahabi
View all publications

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