PE Anti-CD38抗体[FS02] (ab1174)
Key features and details
- PE Mouse monoclonal [FS02] to CD38
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
Related conjugates and formulations
概述
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产品名称
PE Anti-CD38抗体[FS02]
参阅全部 CD38 一抗 -
描述
PE小鼠单克隆抗体[FS02] to CD38 -
宿主
Mouse -
偶联物
PE. Ex: 488nm, Em: 575nm -
特异性
This antibody reacts with a type II membrane glycopeptide with a transmembrane sequence near the NH2-terminus. -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Human -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
Preservative: 0.1% Sodium azide
Constituent: 0.5% BSA -
Concentration information loading... -
克隆
单克隆 -
克隆编号
FS02 -
骨髓瘤
unknown -
同种型
IgG1 -
轻链类型
unknown -
研究领域
相关产品
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Alternative Versions
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Isotype control
应用
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt |
Use 10µl for 106 cells.
ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. HIV Syndromes and other clinical situations characterized by lymphocyte in vivoactivation in human lysed whole peripheral blood or mononuclear cells separated by density gradient. CD38 (PE) immunofluorescence analysis can be performed on a flow cytometerequipped with an excitation source of 488nm and fitted with logarithmic amplifiers. |
| 说明 |
|---|
|
Flow Cyt
Use 10µl for 106 cells. ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. HIV Syndromes and other clinical situations characterized by lymphocyte in vivoactivation in human lysed whole peripheral blood or mononuclear cells separated by density gradient. CD38 (PE) immunofluorescence analysis can be performed on a flow cytometerequipped with an excitation source of 488nm and fitted with logarithmic amplifiers. |
靶标
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功能
Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. -
组织特异性
Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. -
序列相似性
Belongs to the ADP-ribosyl cyclase family. -
发展阶段
Preferentially expressed at both early and late stages of the B and T-cell maturation. It is also detected on erythroid and myeloid progenitors in bone marrow, where the level of surface expression was shown to decrease during differentiation of blast-forming unit E to colony-forming unit E. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 952 Human
- Omim: 107270 Human
- SwissProt: P28907 Human
- Unigene: 479214 Human
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形式
There are 2 isoforms produced by alternative splicing. -
别名
- Acute lymphoblastic leukemia cells antigen CD38 antibody
- ADP ribosyl cyclase 1 antibody
- ADP ribosyl cyclase antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (6)
ab1174 被引用在 6 文献中.
- Xu H et al. GSTM2 alleviates heart failure by inhibiting DNA damage in cardiomyocytes. Cell Biosci 13:220 (2023). PubMed: 38037116
- Panebianco C et al. Counteracting gemcitabine+nab-paclitaxel induced dysbiosis in KRAS wild type and KRASG12D mutated pancreatic cancer in vivo model. Cell Death Discov 9:116 (2023). PubMed: 37019893
- Wen HJ et al. Myeloid Cell-Derived HB-EGF Drives Tissue Recovery After Pancreatitis. Cell Mol Gastroenterol Hepatol 8:173-192 (2019). PubMed: 31125624
- Ramírez T et al. Prevention of aneuploidy by S-adenosyl-methionine in human cells treated with sodium arsenite. Mutat Res 617:16-22 (2007). PubMed: 17241646
- Morra M et al. CD38 is functionally dependent on the TCR/CD3 complex in human T cells. FASEB J 12:581-92 (1998). PubMed: 9576485
- Zupo S et al. CD38 signaling by agonistic monoclonal antibody prevents apoptosis of human germinal center B cells. Eur J Immunol 24:1218-22 (1994). PubMed: 8181532