PE Anti-CD34抗体[MEC 14.7] (ab23830)
Key features and details
- PE Rat monoclonal [MEC 14.7] to CD34
- Suitable for: IHC-P, IP, Flow Cyt
- Reacts with: Mouse
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG2a
Related conjugates and formulations
概述
-
产品名称
PE Anti-CD34抗体[MEC 14.7]
参阅全部 CD34 一抗 -
描述
PE大鼠单克隆抗体[MEC 14.7] to CD34 -
宿主
Rat -
偶联物
PE. Ex: 488nm, Em: 575nm -
特异性
Recognises the murine CD34 cell surface glycoprotein. Murine CD34 is expressed by haematopoietic progenitor cells in the bone marrow, and also by endothelial cells. -
经测试应用
适用于: IHC-P, IP, Flow Cytmore details -
种属反应性
与反应: Mouse -
免疫原
Recombinant full length protein corresponding to Mouse CD34.
Database link: Q64314 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.40
Preservative: 0.09% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading... -
纯度
Protein G purified -
克隆
单克隆 -
克隆编号
MEC 14.7 -
同种型
IgG2a -
研究领域
相关产品
-
Alternative Versions
-
Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab23830于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
1/20 - 1/200.
|
|
| IP |
Use a concentration of 2 - 10 µg/ml.
|
|
| Flow Cyt | (1) |
1/25 - 1/50.
Use 10μl of the suggested working dilution to label 106 cells in 100μl |
| 说明 |
|---|
|
IHC-P
1/20 - 1/200. |
|
IP
Use a concentration of 2 - 10 µg/ml. |
|
Flow Cyt
1/25 - 1/50. Use 10μl of the suggested working dilution to label 106 cells in 100μl |
靶标
-
功能
Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. -
组织特异性
Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues. -
序列相似性
Belongs to the CD34 family. -
发展阶段
On early hematopoietic progenitor cells. -
翻译后修饰
Highly glycosylated.
Phosphorylated on serine residues by PKC. -
细胞定位
Membrane. - Information by UniProt
-
数据库链接
- Entrez Gene: 12490 Mouse
- SwissProt: Q64314 Mouse
- Unigene: 29798 Mouse
-
别名
- CD34 antibody
- CD34 antigen antibody
- CD34 molecule antibody
see all
数据表及文件
-
SDS download
-
Datasheet download
文献 (21)
ab23830 被引用在 21 文献中.
- Guo R et al. Biomimetic composite hydrogel promotes new bone formation in rat bone defects through regulation of miR-19b-3p/WWP1 axis by loaded extracellular vesicles. J Nanobiotechnology 21:459 (2023). PubMed: 38037135
- Vieira JMF et al. Overexpression of mir-135b and mir-210 in mesenchymal stromal cells for the enrichment of extracellular vesicles with angiogenic factors. PLoS One 17:e0272962 (2022). PubMed: 35972944
- Li D et al. Isolation and identification of exosomes from feline plasma, urine and adipose-derived mesenchymal stem cells. BMC Vet Res 17:272 (2021). PubMed: 34384449
- Luo H et al. Manufacturing and banking canine adipose-derived mesenchymal stem cells for veterinary clinical application. BMC Vet Res 17:96 (2021). PubMed: 33648493
- Wei W et al. Bone marrow mesenchymal stem cell exosomes suppress phosphate-induced aortic calcification via SIRT6-HMGB1 deacetylation. Stem Cell Res Ther 12:235 (2021). PubMed: 33849640