PE Anti-CD19抗体[LT19]，prediluted (ab18229)
![Flow Cytometry - PE Anti-CD19 antibody [LT19], prediluted (ab18229)](https://www.abcam.cn/ps/products/18/ab18229/Images/ab18229-279895-anti-cd19-antibody-lt19-prediluted-phycoerythrin-flow-cytometry.jpg "Flow Cytometry - PE Anti-CD19 antibody [LT19], prediluted (ab18229)")
Key features and details
- PE Mouse monoclonal [LT19] to CD19, prediluted
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
概述
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产品名称
PE Anti-CD19抗体[LT19]，prediluted
参阅全部 CD19 一抗 -
描述
PE小鼠单克隆抗体[LT19] to CD19，prediluted -
宿主
Mouse -
偶联物
PE. Ex: 488nm, Em: 575nm -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Human -
免疫原
Tissue, cells or virus corresponding to Human CD19.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.40
Preservative: 0.097% Sodium azide
Constituents: PBS, BSA -
Concentration information loading... -
纯度
Protein G purified -
纯化说明
Conjugate purified by size-exclusion chromatography -
克隆
单克隆 -
克隆编号
LT19 -
同种型
IgG1 -
研究领域
相关产品
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Alternative Versions
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab18229于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt | (1) |
Use at an assay dependent concentration.
20 µl for a 100 µl sample is recommended.
ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
|
| 说明 |
|---|
|
Flow Cyt
Use at an assay dependent concentration. 20 µl for a 100 µl sample is recommended.
ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
|
靶标
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功能
Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. -
疾病相关
Defects in CD19 are the cause of immunodeficiency common variable type 3 (CVID3) [MIM:613493]; also called antibody deficiency due to CD19 defect. CVID3 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low. -
序列相似性
Contains 2 Ig-like C2-type (immunoglobulin-like) domains. -
翻译后修饰
Phosphorylated on serine and threonine upon DNA damage, probably by ATM or ATR. Phosphorylated on tyrosine following B-cell activation. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 930 Human
- Omim: 107265 Human
- SwissProt: P15391 Human
- Unigene: 652262 Human
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别名
- Antibody deficiency due to defect in CD19 antibody
- Antibody deficiency due to defect in CD19, included antibody
- AW495831 antibody
see all
图片
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Flow Cytometry - PE Anti-CD19 antibody [LT19], prediluted (ab18229)
Surface staining of human peripheral blood cells with anti-human CD19 (LT19) PE.
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab18229 被引用在 1 文献中.
- te Vruchte D et al. Relative acidic compartment volume as a lysosomal storage disorder-associated biomarker. J Clin Invest 124:1320-8 (2014). Flow Cyt ; Human . PubMed: 24487591