PE Anti-CD147抗体[MEM-M6/1] (ab77133)
Key features and details
- PE Mouse monoclonal [MEM-M6/1] to CD147
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
Related conjugates and formulations
概述
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产品名称
PE Anti-CD147抗体[MEM-M6/1]
参阅全部 CD147 一抗 -
描述
PE小鼠单克隆抗体[MEM-M6/1] to CD147 -
宿主
Mouse -
偶联物
PE. Ex: 488nm, Em: 575nm -
特异性
ab77133 is a high affinity antibody capable of binding to unstimulated peripheral blood T cells. -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Human -
免疫原
Recombinant fragment corresponding to Human CD147 (Hinge). Protein A-CR purified soluble recombinant form of CD147, CD147Rg, consisting of cDNA coding for the hinge region, CH2 and CH3 domain of Human IgG1. (CD147Rg is secreted by transfectants as a dimer).
Database link: P35613 -
表位
ab77133 recognizes an epitope in the N terminal Ig domain (D1) of CD147. -
阳性对照
- Human blood cells
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.4
Preservative: 0.097% Sodium azide
Constituents: 0.2% BSA, 0.2% PBS
0.2% BSA (high-grade protease free) -
Concentration information loading... -
纯度
Size exclusion -
纯化说明
Purity >95% by SDS-PAGE. -
克隆
单克隆 -
克隆编号
MEM-M6/1 -
同种型
IgG1 -
研究领域
相关产品
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Alternative Versions
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab77133于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt |
Use at an assay dependent concentration.
Use Neat: 20 ul for 100 ul whole blood or 10^6 cells in suspension. ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
| 说明 |
|---|
|
Flow Cyt
Use at an assay dependent concentration. Use Neat: 20 ul for 100 ul whole blood or 10^6 cells in suspension. ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
靶标
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功能
Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). May target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes. -
组织特异性
Present only in vascular endothelium in non-neoplastic regions of the brain, whereas it is present in tumor cells but not in proliferating blood vessels in malignant gliomas. -
序列相似性
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
翻译后修饰
N-glycosylated. -
细胞定位
Cell membrane. Melanosome. Colocalizes with SLC16A1 and SLC16A8 (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV. - Information by UniProt
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数据库链接
- Entrez Gene: 682 Human
- Omim: 109480 Human
- SwissProt: P35613 Human
- Unigene: 501293 Human
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别名
- 5A11 antigen antibody
- 5F7 antibody
- BASI_HUMAN antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab77133 尚未被引用在任何文献中。