AB278595

重组PE Anti-BLNK (phospho Y84)抗体[BLNKY84-H4]

PE Anti-BLNK (phospho Y84) antibody [BLNKY84-H4]

Recombinant
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(1 Publication)

Rabbit Recombinant Monoclonal BLNK phospho Y84 antibody - conjugated to PE. Suitable for Flow Cyt and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human BLNK phospho Y84.

查看别名

BASH, SLP65, BLNK, B-cell linker protein, B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, Cytoplasmic adapter protein, Src homology 2 domain-containing leukocyte protein of 65 kDa, SLP-65

1 Images

Flow Cytometry - PE Anti-BLNK (phospho Y84) antibody [BLNKY84-H4] (AB278595)

Flow Cyt

Supplier Data

Flow Cytometry - PE Anti-BLNK (phospho Y84) antibody [BLNKY84-H4] (AB278595)

Flow cytometric analysis of Daudi cells unstained untreated cells as negative control (blue) or stained untreated (red) or treated with IFNa + IL-4 + pervanadate (green) using ab278595.

不同偶联物与剂型 (3)

Unconjugated

Anti-BLNK (phospho Y84) antibody [BLNKY84-H4]
660 APC

APC Anti-BLNK (phospho Y84) antibody [BLNKY84-H4]
519 FITC

FITC Anti-BLNK (phospho Y84) antibody [BLNKY84-H4]

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

BLNKY84-H4

亚型

IgG

轻链类型

kappa

偶联物

激发波长/发射波长

Ex: 480;565nm, Em: 578nm

不含载体蛋白

反应种属

Human

应用

Flow Cyt

applications

免疫原

Synthetic Peptide within Human BLNK phospho Y84. The exact immunogen used to generate this antibody is proprietary information.

Q8WV28

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "5 µL for 10^6 Cells", "FlowCyt-species-notes": "<p></p>" } } }

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产品详情

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Protein A/G

存储溶液

Preservative: 0.09% Sodium azide Constituents: PBS, 0.2% BSA

运输条件

Blue Ice

储存信息

Store in the dark

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3 (PI3) kinase signaling. May be required for the RAC1-JNK pathway. Plays a critical role in orchestrating the pro-B cell to pre-B cell transition. May play an important role in BCR-induced B-cell apoptosis.

See full target information BLNK phospho Y84

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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Journal of oncology 2021:4391581 PubMed34868313

2021

Baicalin Inhibits EMT through PDK1/AKT Signaling in Human Nonsmall Cell Lung Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Jia Chen,Cheng-Bo Yuan,Bo Yang,Xuan Zhou

View all publications

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Abcam Product Promise

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详情请参阅我们的条款与条件。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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重组PE Anti-BLNK (phospho Y84)抗体[BLNKY84-H4]