Anti-PDLIM2抗体
Anti-PDLIM2 antibody
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(5 Publications)
Rabbit Polyclonal PDLIM2 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Cited in 5 publications. Immunogen corresponding to Recombinant Fragment Protein within Human PDLIM2.
查看别名
PP6345, PDLIM2, PDZ and LIM domain protein 2, PDZ-LIM protein mystique
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PDLIM2 antibody (AB246868)
Paraffin-embedded human placenta tissue stained for PDLIM2 using ab246868 at 1/200 dilution in immunohistochemical analysis.
- ICC/IF
Unknown
Immunocytochemistry/ Immunofluorescence - Anti-PDLIM2 antibody (AB246868)
PFA-fixed, Triton X-100 permeabilized U-2 OS (human bone osteosarcoma epithelial cell line) cells stained for PDLIM2 (green) using ab246868at 4 μg/ml in ICC/IF.
- WB
Unknown
Western blot - Anti-PDLIM2 antibody (AB246868)
All lanes:
Western blot - Anti-PDLIM2 antibody (ab246868) at 0.4 µg/mL
Lane 1:
RT4 (human urinary bladder cancer cell line) whole cell lysate
Lane 2:
U-251 MG (human brain glioma cell line) whole cell lysate
Predicted band size: 37 kDa
false
反应性数据
性能和储存信息
形式
纯化工艺
存储溶液
运输条件
推荐的短期储存时间
推荐的短期储存条件
推荐的长期储存条件
分装信息
储存信息
补充信息
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
PDLIM2 regulates the stability and activity of certain transcription factors and signaling molecules. It acts as an adapter protein to modulate the interaction of actin filaments with these factors. This protein also influences cell motility and adhesion acting as a critical component of a complex involving the actin cytoskeleton. Its regulation of signal transduction and transcription impacts cellular responses and maintenance of tissue integrity.
Pathways
PDLIM2 plays a central role in the NF-kB signaling pathway and the STAT pathway. By controlling the degradation and transport of nuclear factor NF-kB PDLIM2 affects immune responses and inflammation. Similarly it modulates STAT family proteins involved in pathways that trigger responses to cytokines and growth factors. PDLIM2 interacts with proteins such as RelA and STAT3 indicating its function in cell signaling and gene expression regulation.
产品实验方案
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靶点信息
文献 (5)
Recent publications for all applications. Explore the full list and refine your search
Journal of nanobiotechnology 22:548 PubMed39238028
2024
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Cell biochemistry and function 41:542-552 PubMed37170668
2023
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Neoplasma 69:1041-1053 PubMed35723199
2022
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Bioengineered 13:1779-1790 PubMed34713769
2021
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Unspecified reactive species
PLoS pathogens 15:e1007949 PubMed31374104
2019
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Unspecified application
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Unspecified reactive species
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