Anti-PDIA2/PDIP抗体(ab110195)
Key features and details
- Goat polyclonal to PDIA2/PDIP
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-PDIA2/PDIP抗体
参阅全部 PDIA2/PDIP 一抗 -
描述
山羊多克隆抗体to PDIA2/PDIP -
宿主
Goat -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat
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免疫原
Synthetic peptide corresponding to Human PDIA2/PDIP aa 300-400 (internal sequence).
Database link: Q13087 -
阳性对照
- Human Heart and Human Small Intestine tissue. Human Pancreas lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, Tris buffered saline -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab110195于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 0.01 - 0.03 µg/ml. Predicted molecular weight: 57 kDa.
|
|
| IHC-P |
Use a concentration of 3.75 µg/ml.
|
| 说明 |
|---|
|
WB
Use a concentration of 0.01 - 0.03 µg/ml. Predicted molecular weight: 57 kDa. |
|
IHC-P
Use a concentration of 3.75 µg/ml. |
靶标
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功能
Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins. -
组织特异性
Highly expressed in pancreas (at protein level). -
序列相似性
Belongs to the protein disulfide isomerase family.
Contains 2 thioredoxin domains. -
翻译后修饰
The disulfide-linked homodimer exhibits an enhanced chaperone activity.
Glycosylated. -
细胞定位
Endoplasmic reticulum lumen. - Information by UniProt
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数据库链接
- Entrez Gene: 64714 Human
- Entrez Gene: 69191 Mouse
- Entrez Gene: 287164 Rat
- Omim: 608012 Human
- SwissProt: Q13087 Human
- SwissProt: D3Z6P0 Mouse
- SwissProt: P04785 Rat
- Unigene: 66581 Human
see all -
别名
- Pancreas specific protein disulfide isomerase antibody
- Pancreas-specific protein disulfide isomerase antibody
- Pancreatic protein disulfide isomerase antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PDIA2/PDIP antibody (ab110195)
ab110195 at 3.75 µg/ml staining PDIA2/PDIP in Human Heart Formalin-Fixed, Paraffin-Embedded tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PDIA2/PDIP antibody (ab110195)ab110195 at 3.75 µg/ml staining PDIA2/PDIP in Human small intestine Formalin-Fixed, Paraffin-Embedded tissue.
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Western blot - Anti-PDIA2/PDIP antibody (ab110195)Anti-PDIA2/PDIP antibody (ab110195) at 0.03 µg/ml + Human Pancreas lysate at 35 µg
Developed using the ECL technique.
Predicted band size: 57 kDa
Primary incubation was 1 hour
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab110195 被引用在 1 文献中.
- Rawarak N et al. Protein Disulfide Isomerase Inhibitor Suppresses Viral Replication and Production during Antibody-Dependent Enhancement of Dengue Virus Infection in Human Monocytic Cells. Viruses 11:N/A (2019). PubMed: 30781856