Anti-PDE3B抗体(ab42091)
Key features and details
- Goat polyclonal to PDE3B
- Suitable for: WB
- Reacts with: Recombinant fragment
- Isotype: IgG
概述
-
产品名称
Anti-PDE3B抗体
参阅全部 PDE3B 一抗 -
描述
山羊多克隆抗体to PDE3B -
宿主
Goat -
特异性
Does not cross react with PDE4A variants nor with any other PDEs. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Recombinant fragment -
免疫原
Synthetic peptide within Human PDE3B aa 1050 to the C-terminus. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements. Selective for only PDE3B variant.
Database link: Q13370 -
阳性对照
- WB: Human PDE3B protein
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C. -
存储溶液
Antibody stabilization buffer, with preservatives, consisting of Hepes, NaCl, KCl, glycerol, BSA and chaotropic agents. -
Concentration information loading...
-
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab42091于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
1/500. Detects a band of approximately 145 kDa (predicted molecular weight: 145 kDa).
|
说明 |
---|
WB
1/500. Detects a band of approximately 145 kDa (predicted molecular weight: 145 kDa). |
靶标
-
功能
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. -
组织特异性
Abundant in adipose tissues. -
序列相似性
Belongs to the cyclic nucleotide phosphodiesterase family. PDE3 subfamily. -
细胞定位
Membrane. - Information by UniProt
-
别名
- 5''-cyclic phosphodiesterase B antibody
- Adipocyte cAMP phosphodiesterase cGMP inhibited antibody
- AI847709 antibody
see all
图片
数据表及文件
-
Datasheet download
文献 (3)
ab42091 被引用在 3 文献中.
- Guo CH et al. Combination of Fish Oil and Selenium Enhances Anticancer Efficacy and Targets Multiple Signaling Pathways in Anti-VEGF Agent Treated-TNBC Tumor-Bearing Mice. Mar Drugs 19:N/A (2021). PubMed: 33805447
- Yin C et al. PID1 alters the antilipolytic action of insulin and increases lipolysis via inhibition of AKT/PKA pathway activation. PLoS One 14:e0214606 (2019). PubMed: 30990811
- Guo CH et al. Effects of Chinese Medicinal Formula BNG-1 on Phosphodiesterase 3B Expression, Hepatic Steatosis, and Insulin Resistance in High Fat Diet-induced NAFLD Mice. Int J Med Sci 15:1194-1202 (2018). PubMed: 30123057