Anti-Parathyroid Hormone Receptor 1/PTH1R抗体(ab180762)
Key features and details
- Rabbit polyclonal to Parathyroid Hormone Receptor 1/PTH1R
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-Parathyroid Hormone Receptor 1/PTH1R抗体
参阅全部 Parathyroid Hormone Receptor 1/PTH1R 一抗 -
描述
兔多克隆抗体to Parathyroid Hormone Receptor 1/PTH1R -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse, Human
预测可用于: Rat, Cow, Dog, Pig, Orangutan
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免疫原
Recombinant fragment corresponding to Human Parathyroid Hormone Receptor 1/PTH1R (C terminal).
Database link: Q03431 -
阳性对照
- Extracts from Jurkat, MCF7, U251, DU145, THP1 cell lines, mouse kidney and mouse liver tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab180762于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/2000. Predicted molecular weight: 66 kDa.
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| 说明 |
|---|
|
WB
1/500 - 1/2000. Predicted molecular weight: 66 kDa. |
靶标
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功能
Receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. -
组织特异性
Expressed in most tissues. Most abundant in kidney, bone and liver. -
疾病相关
Jansen metaphyseal chondrodysplasia
Chondrodysplasia Blomstrand type
Enchondromatosis multiple
Eiken skeletal dysplasia
Primary failure of tooth eruption -
序列相似性
Belongs to the G-protein coupled receptor 2 family. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 507783 Cow
- Entrez Gene: 403779 Dog
- Entrez Gene: 5745 Human
- Entrez Gene: 19228 Mouse
- Entrez Gene: 100190839 Orangutan
- Entrez Gene: 397675 Pig
- Entrez Gene: 56813 Rat
- Omim: 168468 Human
see all -
别名
- MGC138426 antibody
- MGC138452 antibody
- Parathyroid hormone 1 receptor antibody
see all
图片
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Western blot - Anti-Parathyroid Hormone Receptor 1/PTH1R antibody (ab180762)All lanes : Anti-Parathyroid Hormone Receptor 1/PTH1R antibody (ab180762) at 1/500 dilution
Lane 1 : Extracts from Jurkat cell line
Lane 2 : Extracts from MCF7 cell line
Lane 3 : Extracts from U251 cell line
Lane 4 : Extracts from DU145 cell line
Lane 5 : Extracts from THP1 cell line
Lane 6 : Extracts from mouse kidney tissue
Lane 7 : Extracts from mouse liver tissue
Predicted band size: 66 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab180762 被引用在 1 文献中.
- Qin L et al. Osteocyte β3 integrin promotes bone mass accrual and force-induced bone formation in mice. J Orthop Translat 40:58-71 (2023). PubMed: 37457310