Anti-Parathyroid Hormone Receptor 1/PTH1R抗体(ab176393)
Key features and details
- Rabbit polyclonal to Parathyroid Hormone Receptor 1/PTH1R
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-Parathyroid Hormone Receptor 1/PTH1R抗体
参阅全部 Parathyroid Hormone Receptor 1/PTH1R 一抗 -
描述
兔多克隆抗体to Parathyroid Hormone Receptor 1/PTH1R -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Cow, Dog, Pig, Orangutan
-
免疫原
Synthetic peptide corresponding to Human Parathyroid Hormone Receptor 1/PTH1R aa 388-406 (C terminal).
Sequence:KLRETNAGRCDTRQQYRKL
Database link: Q03431 -
阳性对照
- SKOV, U20S, HeLa and SMMC cell lysates; Human thyroid cancer tissue.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
Preservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azide
Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
-
Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab176393于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 66 kDa.
|
|
| IHC-P |
Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
|
| 说明 |
|---|
|
WB
Use a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 66 kDa. |
|
IHC-P
Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
-
功能
Receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. -
组织特异性
Expressed in most tissues. Most abundant in kidney, bone and liver. -
疾病相关
Jansen metaphyseal chondrodysplasia
Chondrodysplasia Blomstrand type
Enchondromatosis multiple
Eiken skeletal dysplasia
Primary failure of tooth eruption -
序列相似性
Belongs to the G-protein coupled receptor 2 family. -
细胞定位
Cell membrane. - Information by UniProt
-
数据库链接
- Entrez Gene: 507783 Cow
- Entrez Gene: 403779 Dog
- Entrez Gene: 5745 Human
- Entrez Gene: 19228 Mouse
- Entrez Gene: 100190839 Orangutan
- Entrez Gene: 397675 Pig
- Entrez Gene: 56813 Rat
- Omim: 168468 Human
see all -
别名
- MGC138426 antibody
- MGC138452 antibody
- Parathyroid hormone 1 receptor antibody
see all
图片
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Parathyroid Hormone Receptor 1/PTH1R antibody (ab176393)
Immunohistochemical analysis of Paraffin-embedded Human thyroid cancer tissue labeling Parathyroid Hormone Receptor 1/PTH1R with ab176393 at 1 µg/ml.
-
Western blot - Anti-Parathyroid Hormone Receptor 1/PTH1R antibody (ab176393)All lanes : Anti-Parathyroid Hormone Receptor 1/PTH1R antibody (ab176393) at 0.5 µg/ml
Lane 1 : SKOV cell lysates
Lane 2 : U20S cell lysates
Lane 3 : HeLa cell lysates
Lane 4 : SMMC cell lysates
Predicted band size: 66 kDa
实验方案
数据表及文件
-
SDS download
-
Datasheet download
文献 (0)
ab176393 尚未被引用在任何文献中。