Anti-Parathyroid Hormone抗体[B1/70] (ab14496)
Key features and details
- Mouse monoclonal [B1/70] to Parathyroid Hormone
- Suitable for: IHC-Fr, ELISA, IHC-P, RIA
- Reacts with: Human
- Isotype: IgG1
概述
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产品名称
Anti-Parathyroid Hormone抗体[B1/70]
参阅全部 Parathyroid Hormone 一抗 -
描述
小鼠单克隆抗体[B1/70] to Parathyroid Hormone -
宿主
Mouse -
特异性
Ab14496 reacts with parathyroid hormone peptides:aa 15-25; 1-34; 1-38; 1-84; 7-84. There are no cross reactivities with parathyroid hormone peptides: aa 1-3; 1-10; 4-16; 28-48; 39-84; 44-68; 53-84; PTHrP aa 1- 86. -
经测试应用
适用于: IHC-Fr, ELISA, IHC-P, RIAmore details -
种属反应性
与反应: Human
预测可用于: Horse, Cow, Cat, Dog, Pig, Macaque monkey
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免疫原
Poly Lysin conjugated synthetic peptide:
SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNFVALG
, corresponding to amino acids 1-38 of Human Parathyroid Hormone. -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.40
Preservative: 0.05% Sodium azide
Constituent: 0.605% Tris -
Concentration information loading... -
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
B1/70 -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab14496于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-Fr | ||
| ELISA | ||
| IHC-P | ||
| RIA |
| 说明 |
|---|
应用说明
ELISA: Use at a concentration of 1 µg/ml.
IHC-P: Use at a concentration of 2 µg/ml.
IHC-Fr: Use at a concentration of 2 µg/ml.
RIA: Use at a concentration of 25 ng/ml.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
IHC-P: Use at a concentration of 2 µg/ml.
IHC-Fr: Use at a concentration of 2 µg/ml.
RIA: Use at a concentration of 25 ng/ml.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
靶标
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功能
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. -
疾病相关
Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]; also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism. -
序列相似性
Belongs to the parathyroid hormone family. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 280903 Cow
- Entrez Gene: 403986 Dog
- Entrez Gene: 5741 Human
- Entrez Gene: 399502 Pig
- Omim: 168450 Human
- SwissProt: P01268 Cow
- SwissProt: P52212 Dog
- SwissProt: P01270 Human
see all -
别名
- hPTH antibody
- Parathormone antibody
- Parathyrin antibody
see all
数据表及文件
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Datasheet download
文献 (0)
ab14496 尚未被引用在任何文献中。
