AB180159

重组Anti-PAR6抗体[EPR12378] - N-terminal

Anti-PAR6 antibody [EPR12378] - N-terminal

RabMAb
Recombinant
了解详情

Be the first to review this product! Submit a review

(4 Publications)

Rabbit Recombinant Monoclonal PAR6 antibody. N-terminal. Suitable for IP, WB and reacts with Human samples. Cited in 4 publications.

查看别名

PAR6A, PARD6A, Partitioning defective 6 homolog alpha, PAR-6, PAR-6 alpha, PAR-6A, PAR6C, Tax interaction protein 40, TIP-40

2 Images

Supplier Data

Immunoprecipitation - Anti-PAR6 antibody [EPR12378] - N-terminal (AB180159)

Western blot analysis on Immunoprecipitation pellet from either 1) Jurkat cell lysate, or 2) 1xPBS (negative control); showing PAR6, using ab180159 at 1/10 dilution and HRP-conjugated anti-rabbit IgG preferentially detecting the non-reduced form of rabbit IgG.

All lanes:

Immunoprecipitation - Anti-PAR6 antibody [EPR12378] - N-terminal (ab180159)

Predicted band size: 37 kDa

true

Supplier Data

Western blot - Anti-PAR6 antibody [EPR12378] - N-terminal (AB180159)

All lanes:

Western blot - Anti-PAR6 antibody [EPR12378] - N-terminal (ab180159) at 1/1000 dilution

Lane 1:

HeLa cell lysate at 10 µg

Lane 2:

Fetal liver lysate at 10 µg

Lane 3:

293T cell lysate at 10 µg

Lane 4:

Jurkat cell lysate at 10 µg

Lane 5:

Y79 cell lysate at 10 µg

Secondary

All lanes:

Goat anti-rabbit HRP at 1/2000 dilution

Predicted band size: 37 kDa

true

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EPR12378

亚型

IgG

不含载体蛋白

反应种属

Human

应用

IP, WB

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

style

left-column

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "1/10 - 1/100", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Mouse": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

style

left-column

产品详情

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

style

left-column

性能和储存信息

形式

Liquid

纯度

Tissue culture supernatant

存储溶液

pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

style

left-column

style

left-column

style

left-column

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

靶点信息

Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (PubMed : 10873802). Regulates centrosome organization and function. Essential for the centrosomal recruitment of key proteins that control centrosomal microtubule organization (PubMed : 20719959).

See full target information PARD6A

style

left-column

文献 (4)

Recent publications for all applications. Explore the full list and refine your search

Theranostics 11:7262-7275 PubMed34158849

2021

Congenital biliary atresia is correlated with disrupted cell junctions and polarity caused by Cdc42 insufficiency in the liver.

Applications

Unspecified application

Species

Unspecified reactive species

Yongjie Zhou,Hongjie Ji,Qing Xu,Xiaoyun Zhang,Xiaoyue Cao,Yuwei Chen,Mingyang Shao,Zhenru Wu,Jie Zhang,Changli Lu,Jiayin Yang,Yujun Shi,Hong Bu

Nature 556:370-375 PubMed29643508

2018

Aspm knockout ferret reveals an evolutionary mechanism governing cerebral cortical size.

Applications

Unspecified application

Species

Unspecified reactive species

Matthew B Johnson,Xingshen Sun,Andrew Kodani,Rebeca Borges-Monroy,Kelly M Girskis,Steven C Ryu,Peter P Wang,Komal Patel,Dilenny M Gonzalez,Yu Mi Woo,Ziying Yan,Bo Liang,Richard S Smith,Manavi Chatterjee,Daniel Coman,Xenophon Papademetris,Lawrence H Staib,Fahmeed Hyder,Joseph B Mandeville,P Ellen Grant,Kiho Im,Hojoong Kwak,John F Engelhardt,Christopher A Walsh,Byoung-Il Bae

Oncotarget 7:38398-38407 PubMed27223264

2016

H19 long noncoding RNA alters trophoblast cell migration and invasion by regulating TβR3 in placentae with fetal growth restriction.

Applications

Unspecified application

Species

Unspecified reactive species

Lisa Zuckerwise,Jing Li,Lingeng Lu,Yi Men,Tingting Geng,Catalin S Buhimschi,Irina A Buhimschi,Radek Bukowski,Seth Guller,Michael Paidas,Yingqun Huang

Journal of cell science 122:2491-503 PubMed19549684

2009

Rescue of atypical protein kinase C in epithelia by the cytoskeleton and Hsp70 family chaperones.

Applications

Unspecified application

Species

Unspecified reactive species

Anastasia Mashukova,Andrea S Oriolo,Flavia A Wald,M Llanos Casanova,Cornelia Kröger,Thomas M Magin,M Bishr Omary,Pedro J I Salas

View all publications

style

left-column

style

left-column

style

right-column

Abcam Product Promise

我们致力于为您的研究提供高质量的试剂，为您科研的每一步提供支持。若我们的产品未能达到预期性能，我们向您提供 Abcam Product Promise 保障。

详情请参阅我们的条款与条件。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

重组Anti-PAR6抗体[EPR12378] - N-terminal

Anti-PAR6 antibody [EPR12378] - N-terminal

Immunoprecipitation - Anti-PAR6 antibody [EPR12378] - N-terminal (AB180159)

Western blot - Anti-PAR6 antibody [EPR12378] - N-terminal (AB180159)

关键信息

宿主种属

克隆

克隆号

亚型

不含载体蛋白

反应种属

应用

免疫原