重组Anti-P70 S6 Kinase beta/SRK (phospho S371)抗体[EPR2132] (ab109393)
![Western blot - Anti-P70 S6 Kinase beta/SRK (phospho S371) antibody [EPR2132] (ab109393)](https://www.abcam.cn/ps/products/109/ab109393/Images/ab109393-122195-anti-p70-s6-kinase-beta-srk-phospho-s371-antibody-epr2132-western-blot.jpg "Western blot - Anti-P70 S6 Kinase beta/SRK (phospho S371) antibody [EPR2132] (ab109393)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR2132] to P70 S6 Kinase beta/SRK (phospho S371)
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-P70 S6 Kinase beta/SRK (phospho S371)抗体[EPR2132]
参阅全部 P70 S6 Kinase beta/SRK 一抗 -
描述
兔单克隆抗体[EPR2132] to P70 S6 Kinase beta/SRK (phospho S371) -
宿主
Rabbit -
特异性
This antibody only detects p70 S6 Kinase phosphorylated at serine 371. -
经测试应用
适用于: WBmore details
不适用于: Flow Cyt,ICC/IF,IHC-P or IP -
种属反应性
与反应: Human
预测可用于: Mouse, Rat
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免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- 293T cell lysate treated with Alkaline Phosphatase (AP).
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading... -
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EPR2132 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab109393于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/1000 - 1/10000. Predicted molecular weight: 53 kDa.
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| 说明 |
|---|
|
WB
1/1000 - 1/10000. Predicted molecular weight: 53 kDa. |
应用说明
Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
靶标
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功能
Phosphorylates specifically ribosomal protein S6. -
序列相似性
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
Contains 1 AGC-kinase C-terminal domain.
Contains 1 protein kinase domain. -
翻译后修饰
Phosphorylated upon DNA damage, probably by ATM or ATR. - Information by UniProt
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数据库链接
- Entrez Gene: 6199 Human
- Entrez Gene: 58988 Mouse
- Entrez Gene: 361696 Rat
- Omim: 608939 Human
- SwissProt: Q9UBS0 Human
- SwissProt: Q9Z1M4 Mouse
- Unigene: 534345 Human
- Unigene: 271937 Mouse
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别名
- 70 kDa ribosomal protein S6 kinase 2 antibody
- EC 2.7.11.1 antibody
- KS6B2_HUMAN antibody
see all
图片
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Western blot - Anti-P70 S6 Kinase beta/SRK (phospho S371) antibody [EPR2132] (ab109393)All lanes : Anti-P70 S6 Kinase beta/SRK (phospho S371) antibody [EPR2132] (ab109393) at 1/1000 dilution
Lane 1 : 293T cell lysate, untreated
Lane 2 : 293T cell lysate, treated with Alkaline Phosphatase (AP)
Lysates/proteins at 10 µg per lane.
Predicted band size: 53 kDa -
![Anti-P70 S6 Kinase beta/SRK (phospho S371) antibody [EPR2132] (ab109393)](https://www.abcam.cn/ps/products/109/ab109393/Images/ab109393-2-benefits-of-recombinant-antibodies.png)
Anti-P70 S6 Kinase beta/SRK (phospho S371) antibody [EPR2132] (ab109393)
数据表及文件
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SDS download
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Datasheet download
文献 (18)
ab109393 被引用在 18 文献中.
- Chen B et al. SHANK1 facilitates non-small cell lung cancer processes through modulating the ubiquitination of Klotho by interacting with MDM2. Cell Death Dis 13:403 (2022). PubMed: 35468874
- Liu K et al. L-Theanine Regulates the Abundance of Amino Acid Transporters in Mice Duodenum and Jejunum via the mTOR Signaling Pathway. Nutrients 15:N/A (2022). PubMed: 36615799
- Zhang LJ et al. miR-513b-5p inhibits the proliferation and promotes apoptosis of retinoblastoma cells by targeting TRIB1. Open Med (Wars) 16:1364-1371 (2021). PubMed: 34589612
- Guo Y et al. Spontaneous formation of neutrophil extracellular traps is associated with autophagy. Sci Rep 11:24005 (2021). PubMed: 34907287
- Dang N et al. α5-nAChR modulates melanoma growth through the Notch1 signaling pathway. J Cell Physiol 235:7816-7826 (2020). PubMed: 31907929