Anti-p46抗体(ab134556)
Key features and details
- Rabbit polyclonal to p46
- Suitable for: WB, IP
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-p46抗体 -
描述
兔多克隆抗体to p46 -
宿主
Rabbit -
经测试应用
适用于: WB, IPmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Horse, Guinea pig, Cow, Dog, Chimpanzee, Ferret, Rhesus monkey, Gorilla, Chinese hamster, Orangutan, Elephant -
免疫原
Synthetic peptide corresponding to Human p46 aa 371-421.
Database link: NP_115687.2 -
阳性对照
- HeLa, 293T and Jurkat whole cell lysate (ab7899)
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7
Preservative: 0.09% Sodium azide
Constituent: 99% Tris citrate/phosphate
pH 7 to 8. -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
ab134556 is affinity purified using an epitope specific to p46 immobilized on a solid support. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab134556于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/2000 - 1/10000. Predicted molecular weight: 46 kDa.
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IP |
Use a concentration of 2 - 10 µg/ml.
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说明 |
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WB
1/2000 - 1/10000. Predicted molecular weight: 46 kDa. |
IP
Use a concentration of 2 - 10 µg/ml. |
靶标
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功能
Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. -
序列相似性
Contains 1 RRM (RNA recognition motif) domain. -
翻译后修饰
Phosphorylated upon DNA damage, probably by ATM or ATR. -
细胞定位
Nucleus. Nucleus speckle. Cytoplasm. Nucleocytoplasmic shuttling protein. - Information by UniProt
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数据库链接
- Entrez Gene: 84271 Human
- Entrez Gene: 73826 Mouse
- Entrez Gene: 315170 Rat
- Omim: 611520 Human
- SwissProt: Q9BY77 Human
- SwissProt: Q8BG81 Mouse
- Unigene: 709070 Human
- Unigene: 23758 Mouse
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别名
- 46 kDa DNA polymerase delta interaction protein antibody
- DNA polymerase delta interacting protein 3 antibody
- KIAA1649 antibody
see all
图片
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All lanes : Anti-p46 antibody (ab134556) at 0.1 µg/ml
Lane 1 : HeLa whole cell lysate at 50 µg
Lane 2 : HeLa whole cell lysate at 15 µg
Lane 3 : 293T whole cell lysate at 50 µg
Lane 4 : Jurkat whole cell lysate at 50 µg
Developed using the ECL technique.
Predicted band size: 46 kDa
Exposure time: 3 minutes -
Detection of p46 by Western blot of immunprecipitate.
Lane 1: ab134556, at a 1 µg/ml, staining p46 in HeLa whole cell lysate immunoprecipitated using ab134556 at 6 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
Lane 2: The lysate is precipitated with an IgG control antibody.
Detection: Chemiluminescence with an exposure time of 10 seconds.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab134556 尚未被引用在任何文献中。