Anti-OXCT1/SCOT抗体(ab70413)
Key features and details
- Mouse polyclonal to OXCT1/SCOT
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-OXCT1/SCOT抗体
参阅全部 OXCT1/SCOT 一抗 -
描述
小鼠多克隆抗体to OXCT1/SCOT -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Recombinant full length protein within Human OXCT1/SCOT. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements. (NP_000427.1)
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阳性对照
- WB: OXCT1/SCOT transfected 293T cell lysates.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.40
Constituent: 100% PBS -
Concentration information loading... -
纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab70413于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/1000. Predicted molecular weight: 56 kDa.
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| 说明 |
|---|
|
WB
1/500 - 1/1000. Predicted molecular weight: 56 kDa. |
靶标
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功能
Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. -
组织特异性
Abundant in heart, followed in order by kidney, brain, and muscle, whereas in liver it is undetectable; also detectable in leukocytes and fibroblasts. -
通路
Ketone metabolism; succinyl-CoA degradation; acetoacetyl-CoA from succinyl-CoA: step 1/1. -
疾病相关
Succinyl-CoA:3-oxoacid CoA transferase deficiency -
序列相似性
Belongs to the 3-oxoacid CoA-transferase family. -
细胞定位
Mitochondrion matrix. - Information by UniProt
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数据库链接
- Entrez Gene: 5019 Human
- Omim: 601424 Human
- SwissProt: P55809 Human
- Unigene: 278277 Human
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别名
- 3 oxoacid CoA transferase 1 antibody
- 3-oxoacid CoA-transferase 1 antibody
- EC 2.8.3.5 antibody
see all
图片
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Western blot - Anti-OXCT1/SCOT antibody (ab70413)All lanes : Anti-OXCT1/SCOT antibody (ab70413) at 1/500 dilution
Lane 1 : OXCT1/SCOT transfected 293T cell lysate
Lane 2 : Non transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Predicted band size: 56 kDa
Observed band size: 50 kDa why is the actual band size different from the predicted?
数据表及文件
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Datasheet download
文献 (1)
ab70413 被引用在 1 文献中.
- Karwi QG et al. Targeting the glucagon receptor improves cardiac function and enhances insulin sensitivity following a myocardial infarction. Cardiovasc Diabetol 18:1 (2019). PubMed: 30626440
