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AB315500

重组Anti-Orosomucoid 2抗体[EPR26603-23] - BSA and Azide free (Detector)

Anti-Orosomucoid 2 antibody [EPR26603-23] - BSA and Azide free (Detector)

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Rabbit Recombinant Monoclonal Orosomucoid 2 antibody. Carrier free. Suitable for sELISA and reacts with Human samples.

查看别名

AGP2, ORM2, Alpha-1-acid glycoprotein 2, AGP 2, Orosomucoid-2, OMD 2

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Sandwich ELISA - Anti-Orosomucoid 2 antibody [EPR26603-23] - BSA and Azide free (Detector) (AB315500)
  • sELISA

Supplier Data

Sandwich ELISA - Anti-Orosomucoid 2 antibody [EPR26603-23] - BSA and Azide free (Detector) (AB315500)

Sandwich ELISA of ab315498 with the capture antibody dilution at 2 µg/mL and detector antibody dilution at 0.5 µg/mL.

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EPR26603-23

亚型

IgG

不含载体蛋白

Yes

反应种属

Human

应用

sELISA

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

特异性

This antibody does not cross-react with human Orosomucoid 1.

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "sELISA-species-checked": "testedAndGuaranteed", "sELISA-species-dilution-info": "", "sELISA-species-notes": "<p></p>" } } }
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产品详情

ab315500 is a BSA and Azide free antibody supplied in an unconjugated format and it is suitable for sandwich ELISAs to quantify Human Orosomucoid 2. The recommended pair for sandwich ELISA is:

Capture: ab315499, Human Orosomucoid 2 Capture Antibody (unconjugated)

Detector: ab315500, Human Orosomucoid 2 Detector Antibody (unconjugated)

The reference range value is 62.5-4000 pg/mL.

The recommended antibody orientation is based on internal optimization for ELISA based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Please note that the range provided for this antibody is only an estimation based on the performance of the product using the recommended antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody in your assay.

Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency. The antibodies are provided at an approximate concentration of 1 mg/ml as measured by the protein A280 method. Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Sandwich ELISA
The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Please note that the range provided for this antibody is only an estimation based on the performance of the product using the recommended antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody in your assay.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

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性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein A
存储溶液
pH: 7.2 - 7.4 Constituents: PBS
运输条件
Blue Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
+4°C
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

Orosomucoid 2 also known as Alpha-1-acid glycoprotein 2 is a serum glycoprotein with a molecular mass of approximately 41 kDa. The protein is expressed mainly in the liver but it is also present in macrophages and other tissues. It serves primarily as an acute-phase protein during inflammation and other stress responses indicating changes in the concentrations in the blood plasma. Researchers often study it in correlation with Orosomucoid 1 due to the similar roles of these two proteins in the body.
Biological function summary

Orosomucoid 2 involves itself in the modulation of the immune response and drug binding. It binds many drugs and endogenous compounds influencing their bioavailability and activity. As part of the extracellular matrix it interacts with other proteins and structures in the body. The glycosylation of Orosomucoid 2 impacts its binding properties which allows it to react to physiological changes. It does not typically function as part of a larger protein complex.

Pathways

Orosomucoid 2 participates in the acute-phase response and immune system pathways. Its role in the acute-phase response helps regulate inflammation by modulating cytokine activity and leukocyte function. The protein interacts with cytokines like IL-6 and TNF-alpha which are part of these pathways. Orosomucoid 2 also indirectly influences the metabolism and detoxification pathways through its binding capacity and transport of insoluble compounds in the circulatory system.

Orosomucoid 2 associates with conditions such as rheumatoid arthritis and inflammatory bowel disease. In rheumatoid arthritis elevated levels of the protein correlate with inflammation severity playing a part in monitoring disease progression. The protein's interaction with CRP (C-reactive protein) and its involvement in the inflammatory process also links it to inflammatory bowel disease where it can serve as a marker for disease activity. The protein's concentration levels often reflect the presence and intensity of inflammation in these diseases.
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

Functions as a transport protein in the blood stream. Binds various hydrophobic ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability. Appears to function in modulating the activity of the immune system during the acute-phase reaction.
See full target information ORM2
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搭配使用产品

Proteins & Peptides

AB185425

Recombinant Human Orosomucoid 2 protein (His tag)

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Assay Kits

AB315498

Human Orosomucoid 2 Antibody Pair - BSA and Azide free

RabMAb

Sandwich ELISA - Human Orosomucoid 2 Antibody Pair - BSA and Azide free (AB315498)

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  • 0

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