Anti-Ornithine Carbamoyltransferase/OTC抗体[OTI8A1] (ab180401)
Key features and details
- Mouse monoclonal [OTI8A1] to Ornithine Carbamoyltransferase/OTC
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG1
概述
-
产品名称
Anti-Ornithine Carbamoyltransferase/OTC抗体[OTI8A1]
参阅全部 Ornithine Carbamoyltransferase/OTC 一抗 -
描述
小鼠单克隆抗体[OTI8A1] to Ornithine Carbamoyltransferase/OTC -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Cow -
免疫原
Recombinant full length protein corresponding to Human Ornithine Carbamoyltransferase/OTC aa 33-354. Mitochondrial Ornithine carbamoyltransferase (NP_000522)
Sequence:NKVQLKGRDLLTLKNFTGEEIKYMLWLSADLKFRIKQKGEYLPLLQGKSL GMIFEKRSTRTRLSTETGFALLGGHPCFLTTQDIHLGVNESLTDTARVLS SMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQEH YSSLKGLTLSWIGDGNNILHSIMMSAAKFGMHLQAATPKGYEPDASVTKL AEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGQEEEKKKRLQAFQ GYQVTMKTAKVAASDWTFLHCLPRKPEEVDDEVFYSPRSLVFPEAENRKW TIMAVMVSLLTDYSPQLQKPKF
Database link: P00480 -
阳性对照
- Ornithine Carbamoyltransferase/OTC transfected HEK293T cell lysate.
-
常规说明
The clone number has been updated from 8A1 to OTI8A1, both clone numbers name the same clone.
This product was changed from ascites to tissue culture supernatant on 29th May 2018. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 48% PBS, 50% Glycerol, 1% BSA -
Concentration information loading...
-
纯度
Protein G purified -
纯化说明
Purified from TCS -
克隆
单克隆 -
克隆编号
OTI8A1 -
同种型
IgG1 -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
-
Related Products
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab180401于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
1/2000. Predicted molecular weight: 39 kDa.
|
说明 |
---|
WB
1/2000. Predicted molecular weight: 39 kDa. |
靶标
-
组织特异性
Mainly expressed in liver and intestinal mucosa. -
通路
Nitrogen metabolism; urea cycle; L-citrulline from L-ornithine and carbamoyl phosphate: step 1/1. -
疾病相关
Ornithine carbamoyltransferase deficiency -
序列相似性
Belongs to the ATCase/OTCase family. -
翻译后修饰
Acetylation at Lys-88 negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals. -
细胞定位
Mitochondrion matrix. - Information by UniProt
-
数据库链接
- Entrez Gene: 280887 Cow
- Entrez Gene: 5009 Human
- Entrez Gene: 18416 Mouse
- Entrez Gene: 25611 Rat
- Omim: 300461 Human
- SwissProt: Q9N1U7 Cow
- SwissProt: P00480 Human
- SwissProt: P11725 Mouse
see all -
别名
- EC 2.1.3.3 antibody
- MGC129967 antibody
- MGC129968 antibody
see all
图片
-
All lanes : Anti-Ornithine Carbamoyltransferase/OTC antibody [OTI8A1] (ab180401) at 1/2000 dilution
Lane 1 : Non-transfected HEK293T cell lysate
Lane 2 : Lysate of HEK293T cells transfected with the pCMV6-ENTRY Ornithine Carbamoyltransferase / OTC cDNA.
Predicted band size: 39 kDa
HEK293T cell lysates were generated from transient transfection of the cDNA clone (RC221568)
数据表及文件
-
SDS download
-
Datasheet download
文献 (0)
ab180401 尚未被引用在任何文献中。