Anti-Oligodendrocyte Specific蛋白抗体- Oligodendrocyte Marker (ab53041)
Key features and details
- Rabbit polyclonal to Oligodendrocyte Specific Protein - Oligodendrocyte Marker
- Suitable for: ICC, WB
- Reacts with: Mouse, Rat
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-Oligodendrocyte Specific蛋白抗体- Oligodendrocyte Marker
参阅全部 Oligodendrocyte Specific Protein 一抗 -
描述
兔多克隆抗体to Oligodendrocyte Specific蛋白- Oligodendrocyte Marker -
宿主
Rabbit -
特异性
Whilst ab53041 has been generated using synthetic peptide corresponding to human Oligodendrocyte protein (C-terminal), the antibody has only been validated for use in mouse.
Detects endogenous levels of total Oligodendrocyte Specific Protein.
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经测试应用
适用于: ICC, WBmore details -
种属反应性
与反应: Mouse, Rat
预测可用于: Human
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免疫原
Synthetic peptide corresponding to Human Oligodendrocyte Specific Protein (C terminal).
Database link: O75508 -
阳性对照
- WB: Mouse brain extract.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 0.87% Sodium chloride, PBS
Without Mg+2 and Ca+2 -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab53041于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| ICC | (1) |
1/200.
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| WB | (1) |
1/500 - 1/1000. Detects a band of approximately 22 kDa (predicted molecular weight: 22 kDa).
|
| 说明 |
|---|
|
ICC
1/200. |
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WB
1/500 - 1/1000. Detects a band of approximately 22 kDa (predicted molecular weight: 22 kDa). |
靶标
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功能
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. -
序列相似性
Belongs to the claudin family. -
细胞定位
Cell junction > tight junction. Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 5010 Human
- Entrez Gene: 18417 Mouse
- Entrez Gene: 84588 Rat
- Omim: 601326 Human
- SwissProt: O75508 Human
- SwissProt: Q60771 Mouse
- SwissProt: Q99P82 Rat
- Unigene: 31595 Human
see all -
别名
- Claudin 11 antibody
- Claudin-11 antibody
- CLD11_HUMAN antibody
see all
图片
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Western blot - Anti-Oligodendrocyte Specific Protein antibody - Oligodendrocyte Marker (ab53041)All lanes : Anti-Oligodendrocyte Specific Protein antibody - Oligodendrocyte Marker (ab53041) at 1/500 dilution
Lane 1 : Mouse brain extract
Lane 2 : Mouse brain extract with peptide
Predicted band size: 22 kDa
Observed band size: 22 kDaSecondary antibody - anti-rabbit HRP (ab6721)
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (75)
ab53041 被引用在 75 文献中.
- Nishimura Y et al. Early and extensive alterations of glial connexins, distal oligodendrogliopathy type demyelination, and nodal/paranodal pathology are characteristic of multiple system atrophy. Brain Pathol 33:e13131 (2023). PubMed: 36368713
- Plá V et al. Structural characterization of SLYM-a 4th meningeal membrane. Fluids Barriers CNS 20:93 (2023). PubMed: 38098084
- Sreenivasan VKA et al. Single-cell RNA-based phenotyping reveals a pivotal role of thyroid hormone receptor alpha for hypothalamic development. Development 150:N/A (2023). PubMed: 36715020
- Filiou MD et al. Multi-Omics Analysis Reveals Myelin, Presynaptic and Nicotinate Alterations in the Hippocampus of G72/G30 Transgenic Mice. J Pers Med 12:N/A (2022). PubMed: 35207732
- Gargareta VI et al. Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice. Elife 11:N/A (2022). PubMed: 35543322