Anti-OB Cadherin抗体(ab223087)
Key features and details
- Rabbit polyclonal to OB Cadherin
- Suitable for: IHC-P, ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-OB Cadherin抗体
参阅全部 OB Cadherin 一抗 -
描述
兔多克隆抗体to OB Cadherin -
宿主
Rabbit -
经测试应用
适用于: IHC-P, ICC/IFmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Chicken
-
免疫原
Recombinant fragment corresponding to Human OB Cadherin aa 600 to the C-terminus.
Database link: P55287 -
阳性对照
- IHC: Human lung cancer tissue. ICC/IF: PC-3 cells.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol (glycerin, glycerine), PBS -
Concentration information loading... -
纯度
Protein G purified -
纯化说明
Purity >95% -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab223087于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
1/20 - 1/200.
|
|
| ICC/IF |
1/50 - 1/200.
|
| 说明 |
|---|
|
IHC-P
1/20 - 1/200. |
|
ICC/IF
1/50 - 1/200. |
靶标
-
功能
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. -
组织特异性
Expressed mainly in brain but also found in other tissues. Expressed in neuroblasts. -
疾病相关
Note=A chromosomal aberration involving CDH11 is a common genetic feature of aneurysmal bone cyst, a benign osseous neoplasm. Translocation t(16;17)(q22;p13) with USP6. The translocation generates a fusion gene in which the strong CDH11 promoter is fused to the entire USP6 coding sequence, resulting in USP6 transcriptional up-regulation. -
序列相似性
Contains 5 cadherin domains. -
细胞定位
Cell membrane. - Information by UniProt
-
数据库链接
- Entrez Gene: 415797 Chicken
- Entrez Gene: 1009 Human
- Entrez Gene: 12552 Mouse
- Omim: 600023 Human
- SwissProt: O93319 Chicken
- SwissProt: P55287 Human
- SwissProt: P55288 Mouse
- Unigene: 116471 Human
see all -
别名
- CAD11 antibody
- CAD11_HUMAN antibody
- Cadherin 11 antibody
see all
图片
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-OB Cadherin antibody (ab223087)
Paraffin-embedded human lung cancer tissue tissue stained for OB Cadherin using ab223087 at 1/100 dilution in immunohistochemical analysis.
-
Immunocytochemistry/ Immunofluorescence - Anti-OB Cadherin antibody (ab223087)PFA-fixed, Triton X-100 permeabilized PC-3 (human prostate adenocarcinoma cell line) cells stained for OB Cadherin (green) using ab223087 at 1/100 dilution in ICC/IF. Secondary: Alexa Fluor 488® conjugated Goat Anti-Rabbit IgG (H+L).
实验方案
数据表及文件
-
SDS download
-
Datasheet download
文献 (0)
ab223087 尚未被引用在任何文献中。