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AB180167

重组Anti-NUDT19抗体[EPR13162-106]

Anti-NUDT19 antibody [EPR13162-106]

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Rabbit Recombinant Monoclonal NUDT19 antibody. Suitable for WB, ICC/IF and reacts with Human samples.

查看别名

Acyl-coenzyme A diphosphatase NUDT19, Nucleoside diphosphate-linked moiety X motif 19, Nudix motif 19, NUDT19

2 Images
Western blot - Anti-NUDT19 antibody [EPR13162-106] (AB180167)
  • WB

Supplier Data

Western blot - Anti-NUDT19 antibody [EPR13162-106] (AB180167)

All lanes:

Western blot - Anti-NUDT19 antibody [EPR13162-106] (ab180167) at 1/1000 dilution

Lane 1:

K562 cell lysate at 10 µg

Lane 2:

293T cell lysate at 10 µg

Lane 3:

Human ovary lysate at 10 µg

Lane 4:

Human spleen lysate at 10 µg

Secondary

All lanes:

Standard HRP labeled goat anti-rabbit at 1/2000 dilution

Predicted band size: 42 kDa

true

Immunocytochemistry/ Immunofluorescence - Anti-NUDT19 antibody [EPR13162-106] (AB180167)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-NUDT19 antibody [EPR13162-106] (AB180167)

Immunofluorescent analysis of 293T cells labeling NUDT19 with ab180167 at 1/50 dilution (green). DAPI nuclear staining (blue).

不同偶联物与剂型 (1)

  • Carrier free

    Anti-NUDT19 antibody [EPR13162-106] - BSA and Azide free

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EPR13162-106

亚型

IgG

不含载体蛋白

No

反应种属

Human

应用

ICC/IF, WB

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/50 - 1/100", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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产品详情

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein A
存储溶液
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 9% PBS, 0.05% BSA
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

NUDT19 also known as Diphosphatase NUDT19 is a protein that functions by hydrolyzing nucleoside diphosphates which are involved in various biochemical processes such as cell signaling and metabolism. It carries a molecular mass of approximately 22 kDa. NUDT19 mostly expresses in the kidneys and liver playing important roles in detoxification and energy metabolism in these tissues.
Biological function summary

NUDT19 is involved in regulating intracellular levels of Coenzyme A and its derivatives through its enzymatic action. By breaking down these molecules it helps maintain cellular metabolic balance. While it does not function as part of a larger complex its activity directly impacts the availability of metabolic substrates required for energy production and other cellular functions.

Pathways

NUDT19 plays a critical role in the Coenzyme A biosynthesis pathway. It contributes to the regulation of this pathway by controlling the levels of intermediates through its enzymatic activity. This protein links to other key enzymes such as ACSM3 which plays a part in the catabolism of fatty acids. These interactions highlight NUDT19’s involvement in lipid metabolism and energy balance.

NUDT19 has connections to metabolic disorders such as diabetes and fatty liver disease. Abnormal activity or expression of NUDT19 may lead to disruptions in energy metabolism contributing to the pathology of these conditions. Its role in managing Coenzyme A derivatives also ties it to SIRT5 a protein implicated in metabolic regulation and stress responses. Understanding NUDT19’s function could lead to insights into therapeutic strategies for related metabolic disorders.
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate (By similarity). Mediates the hydrolysis of a wide range of CoA esters, including choloyl-CoA and branched-chain fatty-acyl-CoA esters and at low substrate concentrations medium and long-chain fatty-acyl-CoA esters are the primary substrates (By similarity). Highest activity seen with medium-chain acyl-CoA esters and higher rates of activity seen with the unsaturated acyl-CoA esters compared with the saturated esters (By similarity). Exhibits decapping activity towards dpCoA-capped RNAs in vitro (By similarity).
See full target information Nucleoside diphosphate-linked moiety X motif 19
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Abcam Product Promise

我们致力于为您的研究提供高质量的试剂，为您科研的每一步提供支持。若我们的产品未能达到预期性能，我们向您提供 Abcam Product Promise 保障。
详情请参阅我们的条款与条件。
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