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AB190214

Anti-NT5C1A抗体

Anti-NT5C1A antibody

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(3 Publications)

Rabbit Polyclonal NT5C1A antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Synthetic Peptide within Human Cytosolic 5'-nucleotidase 1A aa 150-200.

查看别名

Cytosolic 5'-nucleotidase 1A, cN1A, 5'-deoxynucleotidase, Cytosolic 5'-nucleotidase IA, cN-I, cN-IA, NT5C1A

3 Images
Immunocytochemistry/ Immunofluorescence - Anti-NT5C1A antibody (AB190214)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-NT5C1A antibody (AB190214)

Immunofluorescent analysis of A549 cells labeling NT5C1A using ab190214 at 1/100 dilution. The image on the right is treated with the synthesized peptide.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NT5C1A antibody (AB190214)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NT5C1A antibody (AB190214)

Immunohistochemical analysis of formalin fixed, paraffin embedded Human skeletal muscle tissue labeling NT5C1A using ab190214 at 10 μg/ml.

Western blot - Anti-NT5C1A antibody (AB190214)
  • WB

Supplier Data

Western blot - Anti-NT5C1A antibody (AB190214)

All lanes:

Western blot - Anti-NT5C1A antibody (ab190214) at 1/500 dilution

Lane 1:

MCF7 cell lysate

Lane 2:

HepG2 cell lysate

Lane 3:

MCF7 cell lysate treated with the synthesized peptide

Predicted band size: 41 kDa

false

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

No

反应种属

Human

应用

WB, IHC-P, ICC/IF

applications

免疫原

Synthetic Peptide within Human Cytosolic 5'-nucleotidase 1A aa 150-200. The exact immunogen used to generate this antibody is proprietary information.

Q9BXI3

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搭配使用产品

Primary Antibodies

AB32216

Anti-Insulin degrading enzyme / IDE antibody

KO Validated

Immunohistochemistry (PFA perfusion fixed frozen sections) - Anti-Insulin degrading enzyme / IDE antibody (AB32216)

  • 4
  • 9
Primary Antibodies

AB183734

Anti-GFP antibody [EPR14104]

RabMAb|Recombinant|Lab Essentials|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GFP antibody [EPR14104] (AB183734)

  • 5
  • 24
Primary Antibodies

AB240876

Anti-Kir4.1/KCNJ10 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Kir4.1/KCNJ10 antibody (AB240876)

  • 0
  • 0
Primary Antibodies

AB237716

Anti-IL-5RA antibody [CAL40]

20ul selling size|BOND RX™ Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-5RA antibody [CAL40] (AB237716)

  • 0
  • 0
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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "10 µg/mL", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100 - 1/500", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Immunogen
存储溶液
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

NT5C1A also known as cytosolic 5'-nucleotidase 1A is an enzyme involved in the catabolism of nucleotides. It dephosphorylates nucleoside monophosphates into nucleosides and inorganic phosphate. The molecular mass of NT5C1A is approximately 41 kDa. It is expressed in various tissues with notable presence in muscle tissue and peripheral blood mononuclear cells.
Biological function summary

NT5C1A contributes to the regulation of nucleotide pools in cells impacting DNA and RNA synthesis and degradation processes. It functions independently and does not seem to be a part of a larger complex. Its activity ensures balanced nucleotide levels which is essential for proper cellular function and replication.

Pathways

NT5C1A participates in the purine metabolism pathway by influencing the concentration of nucleosides and nucleotides. It works in coordination with other enzymes such as adenosine deaminase and xanthine oxidase within these metabolic processes. NT5C1A's role is pivotal in maintaining nucleotide homeostasis during cellular proliferation and apoptosis.

NT5C1A has been linked to sporadic inclusion body myositis a muscle disorder characterized by muscle inflammation and weakening. Some studies suggest a connection with autoimmune diseases; however research is still evolving in this area. In these conditions NT5C1A interacts with proteins involved in immune response modulation hinting at its role in disease development.
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

Catalyzes the hydrolysis of ribonucleotide and deoxyribonucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside (PubMed : 11133996, PubMed : 34814800, PubMed : 7599155, PubMed : 8967393). AMP is the major substrate but can also hydrolyze dCMP and IMP (PubMed : 11133996, PubMed : 34814800, PubMed : 7599155, PubMed : 8967393).
See full target information Cytosolic 5'-nucleotidase 1A
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文献 (3)

Recent publications for all applications. Explore the full list and refine your search

Npj viruses 2:6 PubMed40295745

2024

The Wnt/β-catenin pathway is important for replication of SARS-CoV-2 and other pathogenic RNA viruses.

Applications

Unspecified application

Species

Unspecified reactive species

Zaikun Xu,Mohamed Elaish,Cheung Pang Wong,Bardes B Hassan,Joaquin Lopez-Orozco,Alberto Felix-Lopez,Natacha S Ogando,Les Nagata,Lara K Mahal,Anil Kumar,Joyce A Wilson,Ryan Noyce,Irv Mayers,Christopher Power,David Evans,Tom C Hobman

Metabolites 13: PubMed36676954

2022

Urinary ATP Levels Are Controlled by Nucleotidases Released from the Urothelium in a Regulated Manner.

Applications

Unspecified application

Species

Unspecified reactive species

Alejandro Gutierrez Cruz,Mafalda S L Aresta Branco,Brian A Perrino,Kenton M Sanders,Violeta N Mutafova-Yambolieva

Frontiers in physiology 13:918100 PubMed35784885

2022

Mechanosensitive Hydrolysis of ATP and ADP in Lamina Propria of the Murine Bladder by Membrane-Bound and Soluble Nucleotidases.

Applications

Unspecified application

Species

Unspecified reactive species

Mafalda S L Aresta Branco,Alejandro Gutierrez Cruz,Jacob Dayton,Brian A Perrino,Violeta N Mutafova-Yambolieva
View all publications
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