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AB235529

Anti-NOL10 抗体

Anti-NOL10 antibody

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(1 Publication)

Rabbit Polyclonal NOL10 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human NOL10 aa 1-250.

查看别名

Nucleolar protein 10, NOL10

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NOL10 antibody (AB235529)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NOL10 antibody (AB235529)

Paraffin-embedded human pancreas tissue stained for NOL10 using ab235529 at 1/100 dilution in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NOL10 antibody (AB235529)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NOL10 antibody (AB235529)

Paraffin-embedded human small intestine tissue stained for NOL10 using ab235529 at 1/100 dilution in immunohistochemical analysis.

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

No

反应种属

Human

应用

IHC-P, WB

applications

免疫原

Recombinant Fragment Protein within Human NOL10 aa 1-250. The exact immunogen used to generate this antibody is proprietary information.

Q9BSC4

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替代产品

Primary Antibodies

AB181161

Anti-NOL10 antibody [EPR14073-9]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-NOL10 antibody [EPR14073-9] (AB181161)

  • 0
  • 0
Primary Antibodies

AB181160

Anti-NOL10 antibody [EPR14073-8]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-NOL10 antibody [EPR14073-8] (AB181160)

  • 0
  • 0

搭配使用产品

Primary Antibodies

AB5821

Anti-Fibrillarin antibody - Nucleolar Marker

Lab Essentials

Immunocytochemistry/ Immunofluorescence - Anti-Fibrillarin antibody - Nucleolar Marker (AB5821)

  • 5
  • 22
Primary Antibodies

AB252819

Anti-BOP1 antibody [6H11]

Recombinant|Trial Size

Immunocytochemistry/ Immunofluorescence - Anti-BOP1 antibody [6H11] (AB252819)

  • 0
  • 0
Primary Antibodies

AB241578

Anti-UTP18 antibody

Immunoprecipitation - Anti-UTP18 antibody (AB241578)

  • 0
  • 0
Primary Antibodies

AB176842

Anti-Histone H3 antibody [EPR16987] - Nuclear Marker and ChIP Grade

20ul selling size|RabMAb|Recombinant|Lab Essentials|Advanced Validation

Immunocytochemistry/ Immunofluorescence - Anti-Histone H3 antibody [EPR16987] - Nuclear Marker and ChIP Grade (AB176842)

  • 5
  • 15
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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>" } } }
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性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein G
纯化说明
Purity >95%
存储溶液
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

NOL10 also known as nucleolar protein 10 functions primarily in the nucleolus of the cell playing roles in ribosome biogenesis. NOL10 weighs approximately 73 kDa and is present in different human tissues most expressed in spleen and bone marrow. This protein participates in important cellular processes by interacting with ribosomal RNA precursors during ribosome assembly. Its positioning in the nucleolus hints at a focus on ribosome production.
Biological function summary

NOL10 contributes to ribosomal RNA synthesis and processing. It associates with ribosomal RNA processing complexes ensuring mature ribosomal RNA formation. NOL10 works closely with other nucleolar proteins forming part of a larger pre-ribosomal assembly essential for protein synthesis. By doing this NOL10 indirectly supports translation and cell growth.

Pathways

NOL10 is involved in the ribosome biogenesis and RNA processing pathways. It connects with pathways such as the ribosome synthesis pathway interacting with proteins like fibrillarin to promote production of functional ribosomes. It ensures efficient processing within these pathways linking the initial steps of ribosome creation to later stages of protein synthesis.

NOL10's role in ribosome biogenesis links it to conditions like dyskeratosis congenita and certain cancers. Abnormal expression or mutations in NOL10 can result in disrupted ribosomal function contributing to disease progression. It has a connection with proteins such as dyskerin in dyskeratosis congenita highlighting its role in maintaining normal cellular and tissue function.
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

See full target information NOL10
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Cellular oncology (Dordrecht) 46:1493-1507 PubMed37219768

2023

TRIM17-mediated ubiquitination and degradation of RBM38 promotes cisplatin resistance in non-small cell lung cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Tian Zhong,Jing Zhang,Xingren Liu,Hongmin Li
View all publications
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