重组Anti-NMDAR2A抗体[EPR7063] (ab133265)
![Western blot - Anti-NMDAR2A antibody [EPR7063] (ab133265)](https://www.abcam.cn/ps/products/133/ab133265/Images/ab133265-146707-anti-nmdar2a-antibody-epr7063-western-blot.jpg "Western blot - Anti-NMDAR2A antibody [EPR7063] (ab133265)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR7063] to NMDAR2A
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
Related conjugates and formulations
概述
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产品名称
Anti-NMDAR2A抗体[EPR7063]
参阅全部 NMDAR2A 一抗 -
描述
兔单克隆抗体[EPR7063] to NMDAR2A -
宿主
Rabbit -
经测试应用
适用于: WBmore details
不适用于: ICC,IHC-P or IP -
种属反应性
与反应: Mouse, Rat, Human -
免疫原
Recombinant fragment. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- Mouse brain lysate, Rat brain lysate, Human hypothalamus lysate.
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading... -
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EPR7063 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab133265于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/1000 - 1/10000. Detects a band of approximately 180 kDa (predicted molecular weight: 165 kDa).
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| 说明 |
|---|
|
WB
1/1000 - 1/10000. Detects a band of approximately 180 kDa (predicted molecular weight: 165 kDa). |
应用说明
Is unsuitable for ICC,IHC-P or IP.
靶标
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功能
NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits. -
序列相似性
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2A/GRIN2A subfamily. -
细胞定位
Cell membrane. Cell junction > synapse > postsynaptic cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 2903 Human
- Entrez Gene: 14811 Mouse
- Entrez Gene: 24409 Rat
- Omim: 138253 Human
- SwissProt: Q12879 Human
- SwissProt: P35436 Mouse
- SwissProt: Q00959 Rat
- Unigene: 411472 Human
see all -
别名
- EPND antibody
- FESD antibody
- GluN2A antibody
see all
图片
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Western blot - Anti-NMDAR2A antibody [EPR7063] (ab133265)All lanes : Anti-NMDAR2A antibody [EPR7063] (ab133265) at 1/1000 dilution
Lane 1 : Mouse brain lysate
Lane 2 : Rat brain lysate
Lysates/proteins at 10 µg/ml per lane.
Secondary
All lanes : Goat anti-rabbit HRP conjugated antibody at 1/2000 dilution
Predicted band size: 165 kDa -
![Western blot - Anti-NMDAR2A antibody [EPR7063] (ab133265)](https://www.abcam.cn/ps/products/133/ab133265/Images/ab133265-146706-anti-nmdar2a-antibody-epr7063-western-blot.jpg)
Western blot - Anti-NMDAR2A antibody [EPR7063] (ab133265)Anti-NMDAR2A antibody [EPR7063] (ab133265) at 1/1000 dilution + Human hypothalamus lysate at 10 µg
Secondary
Goat anti-rabbit HRP conjugated antibody at 1/2000 dilution
Predicted band size: 165 kDa -
![Anti-NMDAR2A antibody [EPR7063] (ab133265)](https://www.abcam.cn/ps/products/133/ab133265/Images/ab133265-3-benefits-of-recombinant-antibodies.png)
Anti-NMDAR2A antibody [EPR7063] (ab133265)
数据表及文件
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SDS download
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Datasheet download
文献 (20)
ab133265 被引用在 20 文献中.
- Yokokawa T et al. Altered expression of synaptic proteins and adhesion molecules in the hippocampus and cortex following the onset of diabetes in nonobese diabetic mice. Physiol Rep 11:e15673 (2023). PubMed: 37078449
- Hsu YH et al. Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia. iScience 26:106701 (2023). PubMed: 37207277
- Li R et al. Sevoflurane Exposure in the Developing Brain Induces Hyperactivity, Anxiety-Free, and Enhancement of Memory Consolidation in Mice. Front Aging Neurosci 14:934230 (2022). PubMed: 35847668
- Cao W et al. NMDA receptor hypofunction underlies deficits in parvalbumin interneurons and social behavior in neuroligin 3 R451C knockin mice. Cell Rep 41:111771 (2022). PubMed: 36476879
- Su DJ et al. Pra-C exerts analgesic effect through inhibiting microglial activation in anterior cingulate cortex in complete Freund's adjuvant-induced mouse model. Mol Pain 17:1744806921990934 (2021). PubMed: 33590786